HitPredict

Interactor 1: NUDC3 (Q8IVD9)
NudC domain-containing protein 3
Gene: NUDCD3

Interactor 2: KLDC2 (Q9Y2U9)
Kelch domain-containing protein 2 (Hepatocellular carcinoma-associated antigen 33) (Host cell factor homolog LCP) (Host cell factor-like protein 1) (HCLP-1)
Gene: KLHDC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.50	0.630

Property	Details
Experiments	28514442, 33961781, unassigned3799, 25036637
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, luminescence based mammalian interactome mapping
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 361 Hs			1 406
+	Hs
		320830 NUDC3_HUMAN (1-361): 2.03e-159: 452: 100.00		KLH18_HUMAN (87-405): 1.43e-56: 196: 16.16
+	Hs
		1308617 NUDC3_HUMAN (1-361): 2.03e-159: 452: 100.00		KLH20_HUMAN (165-406): 3.17e-50: 180: 13.17
+	Hs
		1235377 NUDC3_HUMAN (1-361): 2.03e-159: 452: 100.00		KLH10_HUMAN (3-278): 1.4e-44: 164: 16.30
+	Hs
		1308590 NUDC3_HUMAN (1-361): 2.03e-159: 452: 100.00		KLHL1_HUMAN (155-405): 1.65e-43: 163: 13.10
+	Hs
		1308608 NUDC3_HUMAN (1-361): 2.03e-159: 452: 100.00		KLHL3_HUMAN (165-400): 1.01e-43: 162: 14.41
+	Hs
		905437 NUDC3_HUMAN (1-361): 2.03e-159: 452: 100.00		HCFC1_HUMAN (3-320): 1.52e-41: 158: 19.77
+	Hs
		1053334 NUDC3_HUMAN (1-361): 2.03e-159: 452: 100.00		Q05C05_HUMAN (3-320): 3.85e-38: 146: 19.77
+	Hs
		1308583 NUDC3_HUMAN (1-361): 2.03e-159: 452: 100.00		KLHL4_HUMAN (228-405): 7.81e-32: 129: 15.17
+	Hs
		1308580 NUDC3_HUMAN (1-361): 2.03e-159: 452: 100.00		KLDC3_HUMAN (5-198): 5.29e-29: 118: 16.84
+	Hs
		1308605 NUDC3_HUMAN (1-361): 2.03e-159: 452: 100.00		KLH13_HUMAN (2-226): 2.22e-26: 113: 15.22
+	Hs
		1308622 NUDC3_HUMAN (1-361): 2.03e-159: 452: 100.00		HCFC2_HUMAN (132-404): 2.85e-26: 113: 17.85
+	Hs
		1198999 NUDC3_HUMAN (1-361): 2.03e-159: 452: 100.00		KLH12_HUMAN (6-156): 1.13e-24: 107: 16.56
+	Hs
		1308556 NUDC3_HUMAN (1-361): 2.03e-159: 452: 100.00		KLDC1_HUMAN (218-405): 1.86e-22: 100: 12.62
+	Hs
		1241901 NUDC3_HUMAN (1-361): 2.03e-159: 452: 100.00		FBX42_HUMAN (212-366): 9.59e-22: 99.5: 25.00
+	Hs
		1308603 NUDC3_HUMAN (1-361): 2.03e-159: 452: 100.00		KLHL9_HUMAN (265-402): 1.9e-12: 70.9: 15.75
+	Hs
		1121448 NUDC3_HUMAN (1-361): 2.03e-159: 452: 100.00		KEAP1_HUMAN (3-98): 1.38e-11: 68.2: 14.58
+	Hs
		1244728 NUDC3_HUMAN (1-361): 2.03e-159: 452: 100.00		KLD10_HUMAN (263-399): 1.35e-11: 67.8: 16.89
+	Hs
		1490540 NUDC_HUMAN (7-343): 2.08e-102: 306: 27.38		HCFC2_HUMAN (132-404): 2.85e-26: 113: 17.85
+	Hs
		1330463 NUDC_HUMAN (7-343): 2.08e-102: 306: 27.38		KLDC1_HUMAN (218-405): 1.86e-22: 100: 12.62
+	Hs
		1241916 NUDC2_HUMAN (191-344): 9.91e-31: 116: 19.11		FBX42_HUMAN (212-366): 9.59e-22: 99.5: 25.00