HitPredict

Interactor 1: RPC3 (Q9BUI4)
DNA-directed RNA polymerase III subunit RPC3 (RNA polymerase III subunit C3) (DNA-directed RNA polymerase III subunit C) (RNA polymerase III 62 kDa subunit) (RPC62)
Gene: POLR3C

Interactor 2: RPC6 (Q9H1D9)
DNA-directed RNA polymerase III subunit RPC6 (RNA polymerase III subunit C6) (DNA-directed RNA polymerase III subunit F) (RNA polymerase III 39 kDa subunit) (RPC39)
Gene: POLR3F

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.853

The method score is based on:

Property Details
Experiments 35271311, 9171375, 21358628
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rpc34~RNA_pol_Rpc82
Common GO terms GO:0003899 - DNA-directed 5'-3' RNA polymerase activity
GO:0005654 - nucleoplasm
GO:0005666 - RNA polymerase III complex
GO:0005829 - cytosol
GO:0006359 - regulation of transcription by RNA polymerase III
and 4 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 534
Hs

1 316
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024