HitPredict

Interactor 1: ENC1 (O14682)
Ectoderm-neural cortex protein 1 (ENC-1) (Kelch-like protein 37) (Nuclear matrix protein NRP/B) (p53-induced gene 10 protein)
Gene: ENC1

Interactor 2: FXL17 (Q9UF56)
F-box/LRR-repeat protein 17 (F-box and leucine-rich repeat protein 17) (F-box only protein 13)
Gene: FBXL17

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	30190310
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	BTB~LRR_6
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0007399 - nervous system development GO:0016567 - protein ubiquitination
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 589 Hs			1 701
+	Hs
		1459087 KLH20_HUMAN (2-584): 1.14e-166: 489: 28.86		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1430059 KLH25_HUMAN (1-589): 8e-162: 476: 74.70		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1199049 KLH12_HUMAN (26-586): 1.78e-157: 464: 27.82		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1333284 KLH23_HUMAN (20-575): 8.31e-81: 266: 29.05		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1459084 KLH21_HUMAN (23-572): 9.44e-72: 243: 30.67		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1312883 KLHL7_HUMAN (36-526): 3.54e-61: 214: 27.89		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1121548 KEAP1_HUMAN (386-589): 3.16e-48: 179: 22.12		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		329116 KLHL2_HUMAN (390-589): 7.01e-44: 166: 26.11		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1459082 KLHL3_HUMAN (440-589): 2.66e-35: 142: 19.21		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1452115 KLH28_HUMAN (348-589): 5.42e-35: 141: 16.73		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1247815 KLH24_HUMAN (373-588): 6.51e-28: 120: 21.10		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1200022 KLH26_HUMAN (367-588): 1.32e-20: 98: 13.98		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1247781 KLH17_HUMAN (473-589): 1.04e-18: 91.8: 21.01		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1459091 IPP_HUMAN (493-589): 1.17e-18: 91.8: 15.09		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1454747 KLH13_HUMAN (508-589): 1.33e-15: 82.2: 19.54		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1454623 KLHL9_HUMAN (508-589): 1.55e-15: 81.8: 20.69		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1235393 KLH10_HUMAN (226-388): 6.69e-09: 60.6: 13.95		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00