HitPredict

Interactor 1: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Interactor 2: YETS2 (Q9ULM3)
YEATS domain-containing protein 2
Gene: YEATS2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	37071664, 37059091
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1834 Hs			1 1422
+	Hs
		1040736 SLX4_HUMAN (1-1834): 0: 1473: 100.00		ENL_HUMAN (203-536): 8.45e-43: 167: 19.38
+	Hs
		775569 SLX4_HUMAN (1-1834): 0: 1473: 100.00		NU214_HUMAN (374-1064): 2.77e-11: 70.8: 17.30
+	Hs
		1129646 SLX4_HUMAN (1-1834): 0: 1473: 100.00		MDC1_HUMAN (746-1345): 4.43e-11: 70: 9.08
+	Hs
		1323708 CRBG2_HUMAN (879-1737): 1.59e-20: 101: 10.81		YETS2_HUMAN (1-1422): 0: 659: 100.00
+	Hs
		161374 KMT2D_HUMAN (769-1409): 5.92e-09: 63.6: 9.52		KDM6A_HUMAN (572-1224): 5.01e-50: 197: 14.92
+	Hs
		340352 SRCAP_HUMAN (982-1802): 3.8e-21: 104: 10.50		YETS4_HUMAN (196-404): 3.62e-40: 150: 26.32
+	Dm
		119660 M9PB30_DROME (814-1463): 1.62e-28: 128: 10.28		M9PB30_DROME (103-878): 1.13e-25: 118: 11.18
+	Hs
		590235 MUC1_HUMAN (870-1755): 3.14e-23: 110: 10.32		MUC1_HUMAN (642-1182): 3.86e-26: 119: 13.90
+	Hs
		1403962 MUC4_HUMAN (850-1813): 9.84e-34: 145: 10.42		MUC4_HUMAN (362-1110): 8.43e-09: 62.7: 18.55
+	Hs
		854358 KI67_HUMAN (889-1833): 6.4e-23: 109: 11.20		CHD7_HUMAN (259-786): 4.45e-13: 76.9: 10.24
+	Hs
		854056 KI67_HUMAN (889-1833): 6.4e-23: 109: 11.20		MDC1_HUMAN (746-1345): 4.43e-11: 70: 9.08
+	Hs
		861240 MAP1B_HUMAN (819-1706): 3.35e-10: 67.8: 10.90		PRG4_HUMAN (157-1022): 1.54e-19: 97.7: 9.92
+	Mm
		1455913 PCLO_MOUSE (836-1825): 7.2e-16: 86.7: 10.09		PCLO_MOUSE (296-1138): 1.47e-13: 78.3: 10.02
+	Hs
		1129588 MDC1_HUMAN (757-1462): 4.4e-17: 90.6: 10.56		MDC1_HUMAN (746-1345): 4.43e-11: 70: 9.08
+	Hs
		1129637 MICA3_HUMAN (1139-1747): 8.47e-13: 76.3: 10.24		MDC1_HUMAN (746-1345): 4.43e-11: 70: 9.08
+	Hs
		1439085 MAGE1_HUMAN (868-1286): 2.87e-11: 70.8: 9.26		MAGE1_HUMAN (652-1227): 5.73e-11: 69.6: 14.62
+	Hs
		161491 KMT2D_HUMAN (769-1409): 5.92e-09: 63.6: 9.52		KMT2C_HUMAN (96-897): 6.92e-13: 76.2: 11.06