HitPredict

Interactor 1: TAB3 (Q8N5C8)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 3) (NF-kappa-B-activating protein 1) (TAK1-binding protein 3) (TAB-3) (TGF-beta-activated kinase 1-binding protein 3)
Gene: TAB3

Interactor 2: DC2I2 (Q96EX3)
Cytoplasmic dynein 2 intermediate chain 2 (Dynein 2 intermediate chain 2) (WD repeat-containing protein 34)
Gene: DYNC2I2

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.573

Property	Details
Experiments	19521662
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 712 Hs			1 536
+	Hs
		1389857 TAB2_HUMAN (1-711): 5.01e-48: 182: 30.53		DC2I2_HUMAN (1-536): 9.46e-110: 339: 100.00
+	Hs
		903169 SMCA2_HUMAN (176-599): 4e-36: 148: 13.59		RBBP7_HUMAN (105-535): 5.44e-75: 245: 14.16
+	Hs
		261449 TAB2_HUMAN (1-711): 5.01e-48: 182: 30.53		TBL1X_HUMAN (97-424): 8.47e-50: 182: 10.13
+	Hs
		1420001 TAB2_HUMAN (1-711): 5.01e-48: 182: 30.53		TBL1R_HUMAN (261-526): 3.12e-47: 173: 12.59
+	Hs
		156574 SYNJ1_HUMAN (245-685): 1.46e-18: 92.9: 11.89		DC1I1_HUMAN (11-536): 6.63e-70: 237: 18.44
+	Hs
		903450 SMCA4_HUMAN (153-599): 5.26e-39: 158: 11.43		FBXW7_HUMAN (35-416): 1.22e-43: 166: 10.43
+	Dm
		1173006 Q9VLS7_DROME (55-541): 2.42e-09: 63.3: 9.25		DYIN_DROME (67-535): 1.07e-77: 259: 20.87
+	Hs
		1273854 MICA3_HUMAN (61-685): 1.09e-27: 122: 10.49		FBXW7_HUMAN (35-416): 1.22e-43: 166: 10.43
+	Mm
		965395 KMT2C_MOUSE (35-571): 5.83e-24: 110: 10.62		WDR5_MOUSE (2-340): 8.33e-50: 176: 11.68
+	Hs
		903336 SMCA4_HUMAN (153-599): 5.26e-39: 158: 11.43		RBBP4_HUMAN (120-383): 7.3e-27: 114: 15.53
+	Hs
		903141 SMCA2_HUMAN (176-599): 4e-36: 148: 13.59		RBBP4_HUMAN (120-383): 7.3e-27: 114: 15.53
+	Dm
		1481151 Q9VLS7_DROME (55-541): 2.42e-09: 63.3: 9.25		FBXW7_DROME (247-535): 1.68e-53: 197: 14.29
+	Hs
		323858 SC31A_HUMAN (220-598): 4.03e-10: 65.5: 13.19		WDR5_HUMAN (2-340): 8.33e-50: 176: 11.68
+	Hs
		1066444 CHAP1_HUMAN (63-511): 1.21e-19: 96: 13.16		RBBP4_HUMAN (120-383): 7.3e-27: 114: 15.53
+	Hs
		1066525 CHD7_HUMAN (1-369): 2.31e-17: 89.1: 14.09		RBBP4_HUMAN (120-383): 7.3e-27: 114: 15.53
+	Hs
		130546 SPT5H_HUMAN (303-505): 2.13e-09: 63.2: 13.79		POC1A_HUMAN (43-347): 2.06e-33: 133: 13.23