HitPredict

Interactor 1: NEK9 (Q8TD19)
Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis A-related kinase 9) (NimA-related protein kinase 9) (NimA-related kinase 8) (Nek8)
Gene: NEK9

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Pkinase
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 979 Hs			1 779
+	Hs
		692133 MARK3_HUMAN (2-481): 1.47e-137: 432: 20.00		PKHA4_HUMAN (1-779): 1.18e-148: 455: 100.00
+	Hs
		1270524 MARK2_HUMAN (1-446): 3.91e-129: 411: 19.46		PKHA4_HUMAN (1-779): 1.18e-148: 455: 100.00
+	Hs
		1093180 STK4_HUMAN (29-485): 1.54e-128: 399: 22.17		PKHA4_HUMAN (1-779): 1.18e-148: 455: 100.00
+	Hs
		1097739 STK3_HUMAN (27-485): 1.25e-128: 399: 19.87		PKHA4_HUMAN (1-779): 1.18e-148: 455: 100.00
+	Hs
		728622 AKT2_HUMAN (6-380): 2.32e-128: 399: 21.52		PKHA4_HUMAN (1-779): 1.18e-148: 455: 100.00
+	Hs
		728428 AKT1_HUMAN (13-376): 2.6e-127: 395: 20.76		PKHA4_HUMAN (1-779): 1.18e-148: 455: 100.00
+	Hs
		909185 NEK4_HUMAN (52-361): 1.16e-56: 213: 36.78		PKHA4_HUMAN (1-779): 1.18e-148: 455: 100.00
+	Hs
		1351876 NEK7_HUMAN (58-304): 2.54e-48: 176: 39.29		PKHA4_HUMAN (1-779): 1.18e-148: 455: 100.00
+	Hs
		317302 STK10_HUMAN (58-308): 1.96e-31: 135: 30.47		PKHA4_HUMAN (1-779): 1.18e-148: 455: 100.00
+	Hs
		1093155 STK4_HUMAN (29-485): 1.54e-128: 399: 22.17		CNKR1_HUMAN (17-356): 5.27e-40: 159: 17.98
+	Hs
		1097719 STK3_HUMAN (27-485): 1.25e-128: 399: 19.87		CNKR1_HUMAN (17-356): 5.27e-40: 159: 17.98
+	Hs
		1106487 MARK2_HUMAN (1-446): 3.91e-129: 411: 19.46		GAB1_HUMAN (52-668): 9.24e-36: 146: 10.87
+	Hs
		728066 AKT1_HUMAN (13-376): 2.6e-127: 395: 20.76		MYH9_HUMAN (136-643): 3.16e-39: 159: 11.86
+	Hs
		728218 AKT1_HUMAN (13-376): 2.6e-127: 395: 20.76		GAB1_HUMAN (52-668): 9.24e-36: 146: 10.87
+	Hs
		909014 NEK4_HUMAN (52-361): 1.16e-56: 213: 36.78		DGKD_HUMAN (34-677): 4.41e-46: 180: 13.91
+	Hs
		772691 NEK4_HUMAN (52-361): 1.16e-56: 213: 36.78		MYH9_HUMAN (136-643): 3.16e-39: 159: 11.86
+	Hs
		772690 NEK2_HUMAN (45-334): 6.34e-52: 191: 36.84		MYH9_HUMAN (136-643): 3.16e-39: 159: 11.86
+	Hs
		1234964 NEK6_HUMAN (58-297): 1.69e-46: 171: 39.68		PKHA7_HUMAN (153-638): 3.81e-34: 143: 23.37
+	Hs
		838937 HERC3_HUMAN (621-763): 1.52e-15: 83.8: 15.86		RHG25_HUMAN (30-181): 3.41e-22: 103: 23.27