HitPredict

Interactor 1: DLG5 (Q8TDM6)
Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG)
Gene: DLG5

Interactor 2: SH3K1 (Q96B97)
SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1)
Gene: SH3KBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0014069 - postsynaptic density GO:0098978 - glutamatergic synapse
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1919 Hs			1 665
+	Hs
		594054 DLG5_HUMAN (1-1919): 0: 879: 100.00		NCK1_HUMAN (104-413): 3.74e-26: 112: 16.62
+	Hs
		222156 DLG5_HUMAN (1-1919): 0: 879: 100.00		NCK2_HUMAN (244-432): 3.03e-17: 86.2: 21.24
+	Hs
		250297 DLG5_HUMAN (1-1919): 0: 879: 100.00		VINEX_HUMAN (67-445): 6.54e-15: 80.5: 19.82
+	Mm
		1223673 DLG4_MOUSE (1177-1916): 1.49e-154: 495: 19.44		SH3K1_MOUSE (1-665): 2.78e-119: 373: 87.87
+	Hs
		1325302 PALS1_HUMAN (1500-1916): 1.31e-98: 336: 18.78		SH3K1_HUMAN (1-665): 1.57e-126: 391: 100.00
+	Hs
		987532 DLG4_HUMAN (1177-1916): 8.05e-155: 496: 19.44		GRB2_HUMAN (2-158): 8.55e-35: 133: 20.37
+	Mm
		1221224 DLG4_MOUSE (1177-1916): 1.49e-154: 495: 19.44		GRB2_MOUSE (2-158): 8.55e-35: 133: 20.37
+	Mm
		237076 DLG4_MOUSE (1177-1916): 1.49e-154: 495: 19.44		NCK2_MOUSE (244-432): 4.01e-16: 82.8: 22.28
+	Mm
		1223547 DLG4_MOUSE (1177-1916): 1.49e-154: 495: 19.44		SRBS1_MOUSE (3-155): 1.1e-13: 77: 34.15
+	Mm
		1223635 DLG4_MOUSE (1177-1916): 1.49e-154: 495: 19.44		SH3R3_MOUSE (201-534): 8.45e-13: 73.9: 11.40
+	Mm
		1190848 DLG4_MOUSE (1177-1916): 1.49e-154: 495: 19.44		SRBS2_MOUSE (3-155): 3.33e-11: 68.9: 30.86
+	Hs
		1384287 ZO2_HUMAN (1347-1499): 3.2e-09: 64.3: 15.06		SH3K1_HUMAN (1-665): 1.57e-126: 391: 100.00
+	Hs
		1458940 ZO2_HUMAN (1347-1499): 3.2e-09: 64.3: 15.06		CD2AP_HUMAN (1-664): 1.84e-95: 309: 32.36
+	Dm
		1061455 Q9VHK4_DROME (1483-1583): 2.95e-11: 71.3: 17.27		GRAP_DROME (2-157): 3.83e-32: 125: 18.01
+	Hs
		1205171 ZO2_HUMAN (1347-1499): 3.2e-09: 64.3: 15.06		SH319_HUMAN (9-367): 1.66e-24: 111: 14.76
+	Hs
		1058852 ZO1_HUMAN (698-816): 5.89e-09: 63.8: 16.81		SH319_HUMAN (9-367): 1.66e-24: 111: 14.76
+	Hs
		1251275 ZO2_HUMAN (1347-1499): 3.2e-09: 64.3: 15.06		DNMBP_HUMAN (4-581): 5.37e-24: 110: 12.50
+	Hs
		1058866 ZO1_HUMAN (698-816): 5.89e-09: 63.8: 16.81		DNMBP_HUMAN (4-581): 5.37e-24: 110: 12.50
+	Hs
		222222 ZO2_HUMAN (1347-1499): 3.2e-09: 64.3: 15.06		NCK2_HUMAN (244-432): 3.03e-17: 86.2: 21.24