HitPredict

Interactor 1: GRAP (Q08012)
Growth factor receptor-bound protein 2 (Downstream of receptor kinase) (Protein enhancer of sevenless 2B)
Gene: drk

Interactor 2: Q9VHK4 (Q9VHK4)
Polychaetoid, isoform B
Gene: pyd

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22028469
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SH2~SH3_2, Guanylate_kin~SH3_1, SH3_1~SH3_2
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 211 Dm			1 1371
+	Hs
		834179 CSK_HUMAN (2-136): 3.19e-25: 103: 36.30		ZO1_HUMAN (1-1280): 0: 653: 29.31
+	Hs
		168615 LYN_HUMAN (3-199): 4e-35: 131: 25.24		CSKP_HUMAN (205-791): 1.41e-98: 339: 13.89
+	Hs
		168616 HCK_HUMAN (3-200): 1.54e-32: 124: 24.65		CSKP_HUMAN (205-791): 1.41e-98: 339: 13.89
+	Hs
		463569 LYN_HUMAN (3-199): 4e-35: 131: 25.24		MPP7_HUMAN (329-793): 5.66e-89: 302: 15.34
+	Hs
		463806 LYN_HUMAN (3-199): 4e-35: 131: 25.24		PALS2_HUMAN (344-791): 6.2e-88: 298: 13.66
+	Hs
		557298 SRC_HUMAN (4-208): 1.27e-32: 124: 25.65		MPP2_HUMAN (346-791): 1.41e-89: 304: 14.66
+	Hs
		440107 LCK_HUMAN (3-200): 4.18e-32: 123: 26.54		MPP7_HUMAN (329-793): 5.66e-89: 302: 15.34
+	Rn
		76720 SRC_RAT (4-208): 9.1e-33: 125: 25.65		PALS1_RAT (243-792): 3.33e-86: 298: 15.54
+	Mm
		1221224 GRB2_MOUSE (1-210): 5.92e-63: 196: 63.08		DLG4_MOUSE (6-299): 3.77e-23: 108: 14.85
+	Hs
		987532 GRB2_HUMAN (1-210): 1.15e-62: 195: 62.62		DLG4_HUMAN (6-299): 5.9e-23: 107: 14.85
+	Hs
		463486 LYN_HUMAN (3-199): 4e-35: 131: 25.24		PTN13_HUMAN (189-632): 2.09e-25: 117: 12.47
+	Hs
		440050 LCK_HUMAN (3-200): 4.18e-32: 123: 26.54		PTN13_HUMAN (189-632): 2.09e-25: 117: 12.47
+	Mm
		431355 SRC_MOUSE (4-208): 1.13e-32: 125: 26.09		DLG4_MOUSE (6-299): 3.77e-23: 108: 14.85
+	Rn
		723904 SRC_RAT (4-208): 9.1e-33: 125: 25.65		DLG4_RAT (6-299): 6.38e-23: 107: 15.18
+	Hs
		463488 LYN_HUMAN (3-199): 4e-35: 131: 25.24		DLG1_HUMAN (6-122): 3.99e-15: 82.9: 30.25
+	Hs
		440052 LCK_HUMAN (3-200): 4.18e-32: 123: 26.54		DLG1_HUMAN (6-122): 3.99e-15: 82.9: 30.25
+	Mm
		440284 LCK_MOUSE (3-200): 6.79e-32: 122: 26.07		DLG1_MOUSE (6-122): 2.24e-14: 80.6: 29.41
+	Hs
		463667 LYN_HUMAN (3-199): 4e-35: 131: 25.24		DLG5_HUMAN (15-159): 1.79e-11: 71.4: 26.85
+	Hs
		440154 LCK_HUMAN (3-200): 4.18e-32: 123: 26.54		DLG5_HUMAN (15-159): 1.79e-11: 71.4: 26.85
+	Hs
		834237 CSK_HUMAN (2-136): 3.19e-25: 103: 36.30		ZO2_HUMAN (379-622): 2.79e-12: 73.7: 18.25