HitPredict

Interactor 1: P85B (O00459)
Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase regulatory subunit beta) (PI3K regulatory subunit beta) (PtdIns-3-kinase regulatory subunit beta) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta) (PI3-kinase subunit p85-beta) (PtdIns-3-kinase regulatory subunit p85-beta)
Gene: PIK3R2

Interactor 2: KRT38 (O76015)
Keratin, type I cuticular Ha8 (Hair keratin, type I Ha8) (Keratin-38) (K38)
Gene: KRT38

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	25416956, 29892012
Identification Methods	two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 728 Hs			1 456
+	Hs
		136245 P85B_HUMAN (1-728): 0: 541: 100.00		K1C14_HUMAN (102-415): 3.24e-147: 429: 52.87
+	Hs
		136374 P85B_HUMAN (1-728): 0: 541: 100.00		K1C17_HUMAN (100-415): 5.87e-99: 305: 52.85
+	Hs
		136287 P85B_HUMAN (1-728): 0: 541: 100.00		K1C15_HUMAN (103-415): 4.27e-96: 298: 52.70
+	Hs
		136265 P85B_HUMAN (1-728): 0: 541: 100.00		K1C16_HUMAN (100-421): 9.58e-95: 295: 51.55
+	Hs
		136398 P85B_HUMAN (1-728): 0: 541: 100.00		K2C79_HUMAN (8-433): 6.84e-85: 272: 22.56
+	Hs
		136278 P85B_HUMAN (1-728): 0: 541: 100.00		K1C10_HUMAN (100-409): 1.19e-82: 267: 50.16
+	Hs
		136314 P85B_HUMAN (1-728): 0: 541: 100.00		K1C20_HUMAN (96-414): 9.04e-84: 265: 45.46
+	Hs
		136336 P85B_HUMAN (1-728): 0: 541: 100.00		K2C6C_HUMAN (67-434): 9.52e-76: 248: 24.87
+	Hs
		136279 P85B_HUMAN (1-728): 0: 541: 100.00		K2C5_HUMAN (67-425): 6.37e-75: 247: 25.76
+	Hs
		300284 HCK_HUMAN (551-724): 3.56e-30: 127: 22.53		KRT34_HUMAN (58-447): 4.8e-156: 449: 60.77
+	Mm
		431354 SRC_MOUSE (535-728): 3.07e-28: 121: 18.81		K1C14_MOUSE (104-415): 7.62e-97: 301: 52.89
+	Mm
		431382 SRC_MOUSE (535-728): 3.07e-28: 121: 18.81		K1C16_MOUSE (104-412): 1.35e-90: 284: 51.46
+	Hs
		362297 ABL1_HUMAN (532-725): 2.37e-30: 130: 21.54		K1H1_HUMAN (55-432): 2.68e-87: 274: 62.96
+	Hs
		473424 HCK_HUMAN (551-724): 3.56e-30: 127: 22.53		K1H1_HUMAN (55-432): 2.68e-87: 274: 62.96
+	Hs
		473435 HCK_HUMAN (551-724): 3.56e-30: 127: 22.53		K1C40_HUMAN (1-432): 3.89e-87: 274: 49.89
+	Hs
		473454 HCK_HUMAN (551-724): 3.56e-30: 127: 22.53		KRT35_HUMAN (1-450): 2.12e-82: 263: 53.98
+	Hs
		557056 SRC_HUMAN (535-728): 2.75e-28: 122: 18.81		K1C10_HUMAN (100-409): 1.19e-82: 267: 50.16
+	Hs
		300546 HCK_HUMAN (551-724): 3.56e-30: 127: 22.53		KRT36_HUMAN (12-455): 3.67e-79: 255: 52.70
+	Hs
		566364 BTK_HUMAN (551-727): 1.81e-31: 132: 20.65		K2C5_HUMAN (67-425): 6.37e-75: 247: 25.76
+	Mm
		431366 SRC_MOUSE (535-728): 3.07e-28: 121: 18.81		K2C5_MOUSE (67-427): 9.36e-74: 244: 25.62