HitPredict

Interactor 1: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Interactor 2: HELLS (Q9NRZ9)
Lymphoid-specific helicase (EC 3.6.4.-) (Proliferation-associated SNF2-like protein) (SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6)
Gene: HELLS

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	19561196, 30737378, 17967891
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 488 Hs			1 838
+	Hs
		1088484 HDAC2_HUMAN (1-488): 0: 707: 100.00		CHD3_HUMAN (50-828): 0: 653: 24.79
+	Hs
		1351278 HDAC2_HUMAN (1-488): 0: 707: 100.00		CHD5_HUMAN (50-835): 0: 632: 24.72
+	Hs
		1132869 HDAC2_HUMAN (1-488): 0: 707: 100.00		CHD4_HUMAN (51-828): 0: 631: 25.27
+	Mm
		1000005 HDAC2_MOUSE (1-488): 0: 704: 99.39		Q5DTP7_MOUSE (51-828): 0: 631: 25.27
+	Mm
		59100 HDAC2_MOUSE (1-488): 0: 704: 99.39		CHD5_MOUSE (48-835): 0: 623: 25.00
+	Hs
		243693 HDAC2_HUMAN (1-488): 0: 707: 100.00		SMCA5_HUMAN (75-833): 0: 613: 30.63
+	Mm
		999997 HDAC2_MOUSE (1-488): 0: 704: 99.39		SMCA4_MOUSE (8-838): 0: 594: 23.43
+	Hs
		903437 HDAC2_HUMAN (1-488): 0: 707: 100.00		SMCA4_HUMAN (8-838): 0: 590: 22.96
+	Hs
		1088327 HDAC1_HUMAN (1-443): 0: 642: 90.07		CHD3_HUMAN (50-828): 0: 653: 24.79
+	Hs
		903216 HDAC2_HUMAN (1-488): 0: 707: 100.00		SMCA2_HUMAN (27-838): 0: 587: 26.37
+	Mm
		148708 HDAC1_MOUSE (1-443): 0: 645: 90.29		CHD4_MOUSE (51-828): 0: 630: 25.27
+	Hs
		1109728 HDAC1_HUMAN (1-443): 0: 642: 90.07		CHD4_HUMAN (51-828): 0: 631: 25.27
+	Mm
		59097 HDAC1_MOUSE (1-443): 0: 645: 90.29		CHD5_MOUSE (48-835): 0: 623: 25.00
+	Hs
		160081 HDAC1_HUMAN (1-443): 0: 642: 90.07		CHD1_HUMAN (47-835): 0: 614: 26.26
+	Dm
		356804 HDAC1_DROME (5-472): 0: 653: 77.92		CHDM_DROME (28-829): 0: 595: 26.52
+	Dm
		1173920 HDAC1_DROME (5-472): 0: 653: 77.92		ISWI_DROME (101-833): 0: 590: 30.07
+	Mm
		148683 HDAC1_MOUSE (1-443): 0: 645: 90.29		SMCA4_MOUSE (8-838): 0: 594: 23.43
+	Hs
		903353 HDAC1_HUMAN (1-443): 0: 642: 90.07		SMCA4_HUMAN (8-838): 0: 590: 22.96
+	Hs
		903150 HDAC1_HUMAN (1-443): 0: 642: 90.07		SMCA2_HUMAN (27-838): 0: 587: 26.37
+	Hs
		1368121 HDAC2_HUMAN (1-488): 0: 707: 100.00		SMRCD_HUMAN (206-744): 1.54e-92: 315: 37.59