Interactor 1: PSN (O02194)
Presenilin homolog (DmPS) (EC 3.4.23.-) (dPS)
Gene: PSN
Interactor 2: PEN2 (Q86BE9)
Gamma-secretase subunit pen-2 (Presenilin enhancer protein 2)
Gene: pen-2
Species: Drosophila melanogaster
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 20421416 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PEN-2~Presenilin |
| Common GO terms | GO:0006509 - membrane protein ectodomain proteolysis GO:0007219 - Notch signaling pathway GO:0007220 - Notch receptor processing GO:0016485 - protein processing GO:0034205 - amyloid-beta formation and 2 others more... |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
