HitPredict

Interactor 1: HMGN2 (P05204)
Non-histone chromosomal protein HMG-17 (High mobility group nucleosome-binding domain-containing protein 2)
Gene: HMGN2

Interactor 2: H2B1J (P06899)
Histone H2B type 1-J (Histone H2B.1) (Histone H2B.r) (H2B/r)
Gene: H2BC11

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34349018, 35575683
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0005634 - nucleus GO:0006325 - chromatin organization GO:0031640 - killing of cells of another organism GO:0061844 - antimicrobial humoral immune response mediated by antimicrobial peptide
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 90 Hs			1 126
+	Hs
		426512 HMGN2_HUMAN (1-90): 3.74e-31: 106: 100.00		H2B2F_HUMAN (1-126): 2.18e-54: 168: 96.83
+	Hs
		426445 HMGN2_HUMAN (1-90): 3.74e-31: 106: 100.00		H2B1O_HUMAN (1-126): 2.8e-54: 167: 98.41
+	Hs
		426564 HMGN2_HUMAN (1-90): 3.74e-31: 106: 100.00		H2B1M_HUMAN (1-126): 4.44e-54: 167: 95.24
+	Hs
		256734 HMGN2_HUMAN (1-90): 3.74e-31: 106: 100.00		H2B1K_HUMAN (1-126): 1.27e-53: 166: 99.21
+	Hs
		426450 HMGN2_HUMAN (1-90): 3.74e-31: 106: 100.00		H2B1B_HUMAN (1-126): 1.42e-53: 166: 97.62
+	Hs
		426465 HMGN2_HUMAN (1-90): 3.74e-31: 106: 100.00		H2BFS_HUMAN (1-126): 9.55e-54: 166: 97.62
+	Hs
		426473 HMGN2_HUMAN (1-90): 3.74e-31: 106: 100.00		H2B1C_HUMAN (1-126): 1.04e-53: 166: 98.41
+	Hs
		426507 HMGN2_HUMAN (1-90): 3.74e-31: 106: 100.00		H2B2E_HUMAN (1-126): 5.71e-54: 166: 99.21
+	Hs
		426548 HMGN2_HUMAN (1-90): 3.74e-31: 106: 100.00		H2B1H_HUMAN (1-126): 5.65e-54: 166: 97.62
+	Hs
		426562 HMGN2_HUMAN (1-90): 3.74e-31: 106: 100.00		H2B1N_HUMAN (1-126): 2.89e-53: 165: 97.62
+	Hs
		426466 HMGN2_HUMAN (1-90): 3.74e-31: 106: 100.00		H2B1D_HUMAN (1-126): 3.08e-53: 164: 97.62
+	Hs
		426565 HMGN2_HUMAN (1-90): 3.74e-31: 106: 100.00		H2B1L_HUMAN (1-126): 2.37e-52: 163: 96.83
+	Hs
		426533 HMGN2_HUMAN (1-90): 3.74e-31: 106: 100.00		H2B3B_HUMAN (1-126): 8.43e-52: 161: 95.24
+	Hs
		426549 HMGN2_HUMAN (1-90): 3.74e-31: 106: 100.00		H2B1A_HUMAN (1-126): 3.41e-46: 147: 84.25
+	Hs
		137419 HMGN4_HUMAN (1-90): 7.98e-22: 82.9: 86.67		H2B1O_HUMAN (1-126): 2.8e-54: 167: 98.41
+	Hs
		137399 HMGN4_HUMAN (1-90): 7.98e-22: 82.9: 86.67		H2B1K_HUMAN (1-126): 1.27e-53: 166: 99.21
+	Hs
		137410 HMGN4_HUMAN (1-90): 7.98e-22: 82.9: 86.67		H2B1J_HUMAN (1-126): 6.16e-54: 166: 100.00
+	Hs
		137421 HMGN4_HUMAN (1-90): 7.98e-22: 82.9: 86.67		H2B1B_HUMAN (1-126): 1.42e-53: 166: 97.62
+	Hs
		137425 HMGN4_HUMAN (1-90): 7.98e-22: 82.9: 86.67		H2BFS_HUMAN (1-126): 9.55e-54: 166: 97.62
+	Hs
		137426 HMGN4_HUMAN (1-90): 7.98e-22: 82.9: 86.67		H2B1D_HUMAN (1-126): 3.08e-53: 164: 97.62