HitPredict

Interactor 1: Q96D37 (Q96D37)
VAV1 protein (Vav guanine nucleotide exchange factor 1)
Gene: VAV1

Interactor 2: NEB2 (Q96SB3)
Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)
Gene: PPP1R9B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	unassigned2213
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 790 Hs			1 817
+	Hs
		584577 VAV_HUMAN (12-790): 0: 605: 99.74		NEB2_HUMAN (1-817): 1.91e-119: 382: 100.00
+	Hs
		1402522 ECT2_HUMAN (34-571): 9.41e-78: 271: 16.90		NEB2_HUMAN (1-817): 1.91e-119: 382: 100.00
+	Hs
		1436548 ECT2_HUMAN (34-571): 9.41e-78: 271: 16.90		NEB1_HUMAN (1-817): 5.25e-106: 352: 46.47
+	Mm
		60104 KALRN_MOUSE (85-744): 1.36e-56: 213: 14.39		Q7TN74_MOUSE (1-817): 2.17e-102: 343: 44.92
+	Hs
		1401936 ECT2_HUMAN (34-571): 9.41e-78: 271: 16.90		ERBIN_HUMAN (11-583): 1.86e-42: 169: 13.82
+	Ce
		145093 VAV_CAEEL (14-787): 1.2e-102: 341: 22.15		UNC89_CAEEL (2-312): 6.31e-20: 98.3: 14.29
+	Hs
		238821 KALRN_HUMAN (85-613): 1.2e-62: 231: 16.42		RIMS1_HUMAN (126-637): 1.04e-44: 176: 17.41
+	Mm
		60064 KALRN_MOUSE (85-744): 1.36e-56: 213: 14.39		H3BJA6_MOUSE (342-543): 3.99e-47: 169: 49.57
+	Hs
		238823 KALRN_HUMAN (85-613): 1.2e-62: 231: 16.42		LNX1_HUMAN (273-773): 1.63e-31: 133: 13.79
+	Hs
		174665 ECT2_HUMAN (34-571): 9.41e-78: 271: 16.90		PDZD2_HUMAN (382-670): 7.91e-16: 84.6: 22.41
+	Hs
		1122348 ECT2_HUMAN (34-571): 9.41e-78: 271: 16.90		SCRIB_HUMAN (412-596): 5.01e-14: 78.7: 21.15
+	Mm
		60118 KALRN_MOUSE (85-744): 1.36e-56: 213: 14.39		DLG2_MOUSE (419-621): 2.96e-28: 123: 21.18
+	Mm
		60096 KALRN_MOUSE (85-744): 1.36e-56: 213: 14.39		DLG4_MOUSE (438-714): 8.52e-28: 122: 16.38
+	Dm
		57928 A1ZBA1_DROME (131-445): 4.13e-15: 82: 23.99		M9NFI9_DROME (255-816): 4.37e-52: 199: 33.45
+	Dm
		1061427 GRAP_DROME (562-787): 4.2e-19: 88.6: 28.63		Q8IPP3_DROME (479-613): 8.4e-40: 161: 34.07
+	Hs
		1121974 ARHG7_HUMAN (706-788): 8.03e-14: 77.5: 28.92		ERBIN_HUMAN (11-583): 1.86e-42: 169: 13.82
+	Mm
		1221224 GRB2_MOUSE (562-782): 4.53e-20: 91.3: 28.25		DLG4_MOUSE (438-714): 8.52e-28: 122: 16.38
+	Hs
		936290 GRB2_HUMAN (732-783): 7.26e-15: 76.3: 48.08		AFAD_HUMAN (411-642): 8.95e-29: 126: 27.69
+	Hs
		987532 GRB2_HUMAN (732-783): 7.26e-15: 76.3: 48.08		DLG4_HUMAN (438-714): 5.31e-28: 122: 16.38
+	Hs
		1121946 ARHG7_HUMAN (706-788): 8.03e-14: 77.5: 28.92		SCRIB_HUMAN (412-596): 5.01e-14: 78.7: 21.15