HitPredict

Interactor 1: ARHGQ (Q96DR7)
Rho guanine nucleotide exchange factor 26 (SH3 domain-containing guanine exchange factor)
Gene: ARHGEF26

Interactor 2: LIN7C (Q9NUP9)
Protein lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3)
Gene: LIN7C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.50	0.650

Property	Details
Experiments	32203420, 26186194, 28514442, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 871 Hs			1 197
+	Hs
		1387791 ARHGQ_HUMAN (1-871): 0: 575: 100.00		LIN7B_HUMAN (1-196): 1.24e-54: 174: 84.69
+	Hs
		168732 ARHGQ_HUMAN (1-871): 0: 575: 100.00		CSKP_HUMAN (13-194): 7.06e-31: 120: 20.53
+	Hs
		1091552 ARHGQ_HUMAN (1-871): 0: 575: 100.00		DLG1_HUMAN (50-178): 6.75e-23: 97.1: 30.60
+	Hs
		1368711 ARHGQ_HUMAN (1-871): 0: 575: 100.00		DLG3_HUMAN (74-164): 8.63e-20: 88.3: 35.42
+	Mm
		92659 D3YYY8_MOUSE (1-871): 0: 554: 86.38		DLG4_MOUSE (14-196): 1.66e-23: 99.1: 22.87
+	Hs
		1218390 ARHGG_HUMAN (180-871): 3.3e-113: 364: 41.44		LIN7C_HUMAN (1-197): 1.56e-57: 181: 100.00
+	Hs
		1104832 ARHGG_HUMAN (180-871): 3.3e-113: 364: 41.44		SNTB2_HUMAN (61-179): 3.01e-32: 123: 35.25
+	Hs
		584588 VAV_HUMAN (363-862): 1.2e-89: 304: 15.88		LIN7C_HUMAN (1-197): 1.56e-57: 181: 100.00
+	Hs
		1091515 ARHGG_HUMAN (180-871): 3.3e-113: 364: 41.44		DLG1_HUMAN (50-178): 6.75e-23: 97.1: 30.60
+	Hs
		1218381 ARHGG_HUMAN (180-871): 3.3e-113: 364: 41.44		LNX1_HUMAN (14-179): 4e-17: 80.6: 22.02
+	Hs
		324292 ARHGF_HUMAN (39-865): 1.35e-101: 336: 24.71		DLG1_HUMAN (50-178): 6.75e-23: 97.1: 30.60
+	Hs
		1006081 ARHG8_HUMAN (386-796): 1.6e-83: 281: 17.90		DLG4_HUMAN (14-196): 4.48e-23: 97.9: 22.87
+	Hs
		1091525 ARHG8_HUMAN (386-796): 1.6e-83: 281: 17.90		DLG1_HUMAN (50-178): 6.75e-23: 97.1: 30.60
+	Hs
		1279514 ARHG8_HUMAN (386-796): 1.6e-83: 281: 17.90		DLG3_HUMAN (74-164): 8.63e-20: 88.3: 35.42
+	Hs
		1279516 ARHG8_HUMAN (386-796): 1.6e-83: 281: 17.90		SNX27_HUMAN (91-175): 2.6e-12: 66.6: 38.14
+	Mm
		1247318 ARHG8_MOUSE (386-791): 3.2e-83: 280: 18.49		MAGI1_MOUSE (94-172): 1.83e-10: 61.2: 36.71
+	Hs
		1279517 ARHG8_HUMAN (386-796): 1.6e-83: 281: 17.90		MAGI1_HUMAN (94-172): 5.43e-10: 60.1: 35.44
+	Mm
		60118 KALRN_MOUSE (438-866): 7.8e-62: 230: 15.75		DLG2_MOUSE (14-196): 1.44e-25: 104: 23.04
+	Mm
		60096 KALRN_MOUSE (438-866): 7.8e-62: 230: 15.75		DLG4_MOUSE (14-196): 1.66e-23: 99.1: 22.87
+	Hs
		238823 KALRN_HUMAN (400-866): 2.68e-62: 232: 14.92		LNX1_HUMAN (14-179): 4e-17: 80.6: 22.02