Protein: ARHGF
Rho guanine nucleotide exchange factor 15 (Ephexin-5) (E5) (Vsm-RhoGEF)

Gene: ARHGF, ARHGEF15
Organism: Homo sapiens
Interactions: 47
UniProt ID: O94989

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005096 - GTPase activator activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0030425 - dendrite

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

324301

CEP55
Centrosomal protein of 55 kDa

4

1

High-throughput

0.705

High

324287

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.647

High

324288

RHOA
Transforming protein RhoA

1

20

High-throughput

0.647

High

324304

SH3R1
E3 ubiquitin-protein ligase SH3RF1

1

15

High-throughput

0.621

High

324286

EPHA4
Ephrin type-A receptor 4

1

20

Small-scale

0.618

High

324292

DLG1
Disks large homolog 1

1

10

Small-scale

0.618

High

324294

KGP1
cGMP-dependent protein kinase 1

2

13

High-throughput

0.606

High

324297

LASP1
LIM and SH3 domain protein 1

1

9

High-throughput

0.573

High

324314

GORS2
Golgi reassembly-stacking protein 2

2

2

High-throughput

0.553

High

324293

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

0

High-throughput

0.549

High

324313

CSTP1
Centriolar satellite-associated tubulin polyglutamylase complex regulator 1

1

0

High-throughput

0.518

High

324317

PHOCN
MOB-like protein phocein

1

0

High-throughput

0.518

High

324306

BICD2
Protein bicaudal D homolog 2

1

11

High-throughput

0.515

High

324312

DNJC5
DnaJ homolog subfamily C member 5

1

3

High-throughput

0.501

High

251489

CCNT1
Cyclin-T1

1

1

High-throughput

0.479

High

324276

PTMA
Prothymosin alpha [Cleaved into: Prothymosin alpha, N-terminally processed; Thymosin alpha-1]

1

1

High-throughput

0.479

High

324278

EZRI
Ezrin

1

13

High-throughput

0.479

High

324281

MOES
Moesin

1

13

High-throughput

0.479

High

324282

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

3

High-throughput

0.479

High

324283

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

2

High-throughput

0.479

High

324285

CDK7
Cyclin-dependent kinase 7

1

2

High-throughput

0.479

High

324290

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

7

High-throughput

0.479

High

324291

UBE3A
Ubiquitin-protein ligase E3A

1

4

Small-scale

0.479

High

324295

UBP2L
Ubiquitin-associated protein 2-like

1

2

High-throughput

0.479

High

324296

SCRIB
Protein scribble homolog

1

12

High-throughput

0.479

High

324298

KIF14
Kinesin-like protein KIF14

1

9

High-throughput

0.479

High

324300

DDB1
DNA damage-binding protein 1

1

1

High-throughput

0.479

High

324305

DDX42
ATP-dependent RNA helicase DDX42

1

1

High-throughput

0.479

High

324307

PSPC1
Paraspeckle component 1

1

2

High-throughput

0.479

High

324315

SYFA
Phenylalanine--tRNA ligase alpha subunit

1

1

High-throughput

0.479

High

324316

SGT1
Protein SGT1 homolog

1

1

High-throughput

0.479

High

324279

H15
Histone H1.5

1

1

High-throughput

0.470

High

324308

P5CR2
Pyrroline-5-carboxylate reductase 2

1

0

High-throughput

0.458

High

324310

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

0

High-throughput

0.458

High

324289

ERR3
Estrogen-related receptor gamma

1

16

High-throughput

0.439

High

229604

CALU
Calumenin

1

2

High-throughput

0.437

High

324277

KCRU
Creatine kinase U-type, mitochondrial

1

1

High-throughput

0.437

High

324280

TYY1
Transcriptional repressor protein YY1

1

1

High-throughput

0.437

High

324284

RADI
Radixin

1

13

High-throughput

0.437

High

324299

RCN1
Reticulocalbin-1

1

2

High-throughput

0.437

High

324302

ZN326
DBIRD complex subunit ZNF326

1

1

High-throughput

0.437

High

324309

PP1RA
Serine/threonine-protein phosphatase 1 regulatory subunit 10

1

2

High-throughput

0.437

High

324311

SF3B5
Splicing factor 3B subunit 5

1

3

High-throughput

0.437

High

324318

RT23
Small ribosomal subunit protein mS23

1

1

High-throughput

0.437

High

324319

TRRAP
Transformation/transcription domain-associated protein

1

3

High-throughput

0.437

High

298640

ATP5H
ATP synthase peripheral stalk subunit d, mitochondrial

1

0

High-throughput

0.249

Low

324303

FA76B
Protein FAM76B

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025