Interactor 1: SEH1 (Q96EE3)
Nucleoporin SEH1 (GATOR2 complex protein SEH1) (Nup107-160 subcomplex subunit SEH1) (SEC13-like protein)
Gene: SEH1L

Interactor 2: MIOS (Q9NXC5)
GATOR2 complex protein MIOS (Missing oocyte meiosis regulator homolog)
Gene: MIOS

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 26496610, 35831510
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains MIOS_WD40~WD40, WD40~zinc_ribbon_16
Common GO terms GO:0005765 - lysosomal membrane
GO:0005829 - cytosol
GO:0031503 - protein-containing complex localization
GO:0031669 - cellular response to nutrient levels
GO:0034198 - cellular response to amino acid starvation
and 3 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 360
Hs

1 875
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Service provided by Combinatics, Japan

Last updated: 11Aug2025