HitPredict

Interactor 1: BCL9 (O00512)
B-cell CLL/lymphoma 9 protein (B-cell lymphoma 9 protein) (Bcl-9) (Protein legless homolog)
Gene: BCL9

Interactor 2: LHX1 (P48742)
LIM/homeobox protein Lhx1 (LIM homeobox protein 1) (Homeobox protein Lim-1) (hLim-1)
Gene: LHX1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006366 - transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1426 Hs			1 406
+	Hs
		139030 BCL9_HUMAN (1-1426): 4.48e-144: 478: 100.00		LHX3_HUMAN (1-377): 7.9e-56: 190: 33.42
+	Hs
		139017 BCL9_HUMAN (1-1426): 4.48e-144: 478: 100.00		LHX4_HUMAN (1-398): 1.6e-54: 187: 31.97
+	Hs
		138988 BCL9_HUMAN (1-1426): 4.48e-144: 478: 100.00		ISL1_HUMAN (1-347): 1.43e-50: 175: 27.07
+	Hs
		138982 BCL9_HUMAN (1-1426): 4.48e-144: 478: 100.00		LHX2_HUMAN (2-317): 6.48e-48: 169: 26.84
+	Hs
		139032 BCL9_HUMAN (1-1426): 4.48e-144: 478: 100.00		LHX6_HUMAN (2-314): 2.57e-46: 164: 27.62
+	Hs
		139018 BCL9_HUMAN (1-1426): 4.48e-144: 478: 100.00		ISL2_HUMAN (4-346): 9.97e-44: 157: 26.51
+	Hs
		139007 BCL9_HUMAN (1-1426): 4.48e-144: 478: 100.00		LHX8_HUMAN (3-318): 2.73e-43: 156: 27.67
+	Hs
		877533 KMT2C_HUMAN (143-1069): 6.77e-17: 89.4: 13.40		LHX1_HUMAN (1-406): 1.75e-90: 280: 100.00
+	Hs
		877571 CHD7_HUMAN (439-1029): 9.05e-15: 82.4: 11.30		LHX1_HUMAN (1-406): 1.75e-90: 280: 100.00
+	Hs
		1368505 CBP_HUMAN (179-1264): 2.43e-29: 130: 12.05		LHX3_HUMAN (1-377): 7.9e-56: 190: 33.42
+	Mm
		312712 F186A_MOUSE (1-1091): 6.4e-25: 115: 10.12		LMX1B_MOUSE (2-347): 1.16e-51: 179: 29.48
+	Hs
		1338282 KMT2C_HUMAN (143-1069): 6.77e-17: 89.4: 13.40		LHX3_HUMAN (1-377): 7.9e-56: 190: 33.42
+	Hs
		1289050 BCL9L_HUMAN (4-1216): 2.03e-17: 90.9: 9.74		LHX4_HUMAN (1-398): 1.6e-54: 187: 31.97
+	Hs
		1338264 KMT2C_HUMAN (143-1069): 6.77e-17: 89.4: 13.40		LHX4_HUMAN (1-398): 1.6e-54: 187: 31.97
+	Hs
		961482 BCL9L_HUMAN (4-1216): 2.03e-17: 90.9: 9.74		ISL1_HUMAN (1-347): 1.43e-50: 175: 27.07
+	Hs
		895747 BCL9L_HUMAN (4-1216): 2.03e-17: 90.9: 9.74		LHX2_HUMAN (2-317): 6.48e-48: 169: 26.84
+	Hs
		895758 KMT2C_HUMAN (143-1069): 6.77e-17: 89.4: 13.40		LHX2_HUMAN (2-317): 6.48e-48: 169: 26.84
+	Hs
		1289058 BCL9L_HUMAN (4-1216): 2.03e-17: 90.9: 9.74		LHX6_HUMAN (2-314): 2.57e-46: 164: 27.62
+	Hs
		895809 CHD7_HUMAN (439-1029): 9.05e-15: 82.4: 11.30		LHX2_HUMAN (2-317): 6.48e-48: 169: 26.84
+	Hs
		1289051 BCL9L_HUMAN (4-1216): 2.03e-17: 90.9: 9.74		ISL2_HUMAN (4-346): 9.97e-44: 157: 26.51