Interactor 1: CSN4 (Q9BT78)
COP9 signalosome complex subunit 4 (SGN4) (Signalosome subunit 4) (JAB1-containing signalosome subunit 4)
Gene: COPS4
Interactor 2: CSN3 (Q9UNS2)
COP9 signalosome complex subunit 3 (SGN3) (Signalosome subunit 3) (JAB1-containing signalosome subunit 3)
Gene: COPS3
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.976 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26186194, 28514442, 32034103, 33961781, 16036220, 20399188, 19295130, 24981860, 25043011, 9535219, unassigned3799 |
| Identification Methods | affinity chromatography technology, pull down, chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CSN4_RPN5_eIF3a~PCI, COP9_hel_rpt~PCI, PCI~PCI, PCI~PSMD12-CSN4_N |
| Common GO terms | GO:0000338 - protein deneddylation GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol and 3 others more... |
| Homologous interactions | 18 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
