HitPredict

Interactor 1: PACN1 (Q9BY11)
Protein kinase C and casein kinase substrate in neurons protein 1 (Syndapin-1)
Gene: PACSIN1

Interactor 2: 3BP1 (Q9Y3L3)
SH3 domain-binding protein 1
Gene: SH3BP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007015 - actin filament organization
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 444 Hs			1 701
+	Hs
		1229256 PACN1_HUMAN (1-444): 2.84e-95: 295: 100.00		RHG17_HUMAN (2-701): 3.51e-116: 371: 36.89
+	Hs
		1462295 PACN2_HUMAN (1-444): 3.13e-79: 255: 60.70		3BP1_HUMAN (1-701): 5.26e-129: 399: 100.00
+	Hs
		1150901 CIP4_HUMAN (18-391): 2.41e-42: 159: 14.82		3BP1_HUMAN (1-701): 5.26e-129: 399: 100.00
+	Hs
		1150860 CIP4_HUMAN (18-391): 2.41e-42: 159: 14.82		RHG44_HUMAN (2-684): 5.33e-119: 377: 37.63
+	Hs
		1150865 CIP4_HUMAN (18-391): 2.41e-42: 159: 14.82		RHG17_HUMAN (2-701): 3.51e-116: 371: 36.89
+	Hs
		212744 SRGP3_HUMAN (25-408): 1.36e-37: 147: 11.89		SRGP3_HUMAN (4-699): 1.24e-106: 350: 16.09
+	Hs
		1165232 FBP1L_HUMAN (250-443): 3.36e-10: 64: 14.29		RHG44_HUMAN (2-684): 5.33e-119: 377: 37.63
+	Hs
		1229254 FNBP1_HUMAN (322-443): 3.32e-09: 60.9: 21.31		RHG17_HUMAN (2-701): 3.51e-116: 371: 36.89
+	Hs
		212750 SRGP3_HUMAN (25-408): 1.36e-37: 147: 11.89		SRGP2_HUMAN (4-684): 8.95e-82: 282: 14.77
+	Hs
		269575 SRGP1_HUMAN (26-408): 1.97e-36: 144: 12.41		SRGP2_HUMAN (4-684): 8.95e-82: 282: 14.77
+	Dm
		118395 M9NE16_DROME (18-407): 1.14e-35: 141: 11.72		RG92B_DROME (2-687): 7.23e-81: 274: 25.11
+	Hs
		1150873 CIP4_HUMAN (18-391): 2.41e-42: 159: 14.82		RHG12_HUMAN (13-462): 3.04e-71: 250: 17.73
+	Hs
		1150861 CIP4_HUMAN (18-391): 2.41e-42: 159: 14.82		Q1RLN5_HUMAN (35-469): 4.35e-69: 243: 17.66
+	Hs
		212777 SRGP3_HUMAN (25-408): 1.36e-37: 147: 11.89		RHG24_HUMAN (182-618): 8.6e-71: 246: 18.30
+	Hs
		65904 CRKL_HUMAN (366-444): 7.43e-12: 68: 32.91		RHG42_HUMAN (3-687): 3.49e-88: 297: 14.57
+	Hs
		67633 CRKL_HUMAN (366-444): 7.43e-12: 68: 32.91		RHG32_HUMAN (261-689): 2.79e-75: 267: 22.20
+	Mm
		1225301 ITSN1_MOUSE (353-442): 8e-09: 60.1: 24.44		RHG30_MOUSE (258-694): 6.51e-73: 258: 24.89
+	Hs
		1061252 SRGP1_HUMAN (26-408): 1.97e-36: 144: 12.41		RHG01_HUMAN (274-433): 9.54e-21: 97.4: 38.42
+	Hs
		539970 CRKL_HUMAN (366-444): 7.43e-12: 68: 32.91		BCR_HUMAN (273-438): 1.06e-18: 93.2: 34.52