HitPredict

Interactor 1: UN45A (Q9H3U1)
Protein unc-45 homolog A (Unc-45A) (GCUNC-45) (Smooth muscle cell-associated protein 1) (SMAP-1)
Gene: UNC45A

Interactor 2: ALK (Q9UM73)
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Gene: ALK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	35384245, 34273398
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 944 Hs			1 1620
+	Hs
		1405818 TTC1_HUMAN (18-172): 4.98e-40: 151: 29.75		ALK_HUMAN (1-1620): 0: 1901: 100.00
+	Hs
		1461995 CHIP_HUMAN (8-159): 2.16e-35: 138: 29.30		ALK_HUMAN (1-1620): 0: 1901: 100.00
+	Hs
		711941 UN45A_HUMAN (1-944): 0: 1040: 100.00		LTK_HUMAN (606-1458): 2.7e-178: 559: 53.24
+	Hs
		650414 UN45A_HUMAN (1-944): 0: 1040: 100.00		FGFR3_HUMAN (952-1449): 2.13e-119: 397: 26.31
+	Hs
		412606 UN45A_HUMAN (1-944): 0: 1040: 100.00		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		464027 SGTB_HUMAN (16-141): 1.37e-38: 147: 33.33		RET_HUMAN (804-1477): 5.87e-139: 460: 23.15
+	Hs
		650487 CHIP_HUMAN (8-159): 2.16e-35: 138: 29.30		FGFR3_HUMAN (952-1449): 2.13e-119: 397: 26.31
+	Hs
		439879 CHIP_HUMAN (8-159): 2.16e-35: 138: 29.30		INSR_HUMAN (973-1436): 1e-112: 392: 34.25
+	Hs
		650279 TMTC1_HUMAN (3-251): 1.29e-16: 87.2: 11.42		FGFR3_HUMAN (952-1449): 2.13e-119: 397: 26.31
+	Rn
		205568 STIP1_RAT (4-239): 9.7e-18: 89.9: 15.44		INSR_RAT (973-1484): 1.46e-112: 392: 32.38
+	Dm
		561267 Q9VH81_DROME (6-199): 3.24e-38: 152: 20.62		7LESS_DROME (1022-1417): 2.19e-67: 254: 36.34
+	Hs
		412617 RPAP3_HUMAN (15-343): 2.4e-41: 164: 16.77		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		411635 PPP5_HUMAN (10-224): 4.53e-40: 157: 20.47		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		412806 CHIP_HUMAN (8-159): 2.16e-35: 138: 29.30		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		411449 STIP1_HUMAN (4-239): 3.45e-18: 91: 15.44		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		185345 OGT1_HUMAN (91-491): 1.95e-12: 73.7: 13.30		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		317971 TOM70_HUMAN (12-181): 6.12e-09: 61.8: 14.29		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07