Protein: CKS1
Cyclin-dependent kinases regulatory subunit (Cell division control protein CKS1)

Gene: CKS1
Organism: Saccharomyces cerevisiae S288C
Interactions: 65
UniProt ID: P20486

Gene Ontology (top 5):
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0007346 - regulation of mitotic cell cycle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

364323

CDK1
Cyclin-dependent kinase 1

18

20

Small-scale

0.988

High

633243

SWE1
Mitosis inhibitor protein kinase SWE1

2

3

Small-scale

0.799

High

633230

CKS1
Cyclin-dependent kinases regulatory subunit

2

5

Small-scale

0.755

High

633235

CG23
G2/mitotic-specific cyclin-3

7

20

Small-scale

0.750

High

633234

CG22
G2/mitotic-specific cyclin-2

8

20

Small-scale

0.746

High

632401

CG12
G1/S-specific cyclin CLN2

6

20

Small-scale

0.733

High

633252

SIC1
Protein SIC1

7

0

Small-scale

0.714

High

632384

CG11
G1/S-specific cyclin CLN1

4

20

High-throughput

0.702

High

633238

CGS5
S-phase entry cyclin-5

4

20

Small-scale

0.694

High

633233

CG21
G2/mitotic-specific cyclin-1

3

20

High-throughput

0.674

High

479247

CDC6
Cell division control protein 6

3

1

Small-scale

0.641

High

633258

SSB2
Ribosome-associated molecular chaperone SSB2

3

1

High-throughput

0.634

High

633236

CG24
G2/mitotic-specific cyclin-4

2

20

High-throughput

0.606

High

509389

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

2

0

Small-scale

0.569

High

633248

SRL3
Protein SRL3

2

0

High-throughput

0.563

High

633266

CIP1
Cyclin-dependent kinase inhibitor CIP1

2

0

High-throughput

0.563

High

525900

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.552

High

633262

RTF1
RNA polymerase-associated protein RTF1

1

0

Small-scale

0.537

High

633242

CGS6
S-phase entry cyclin-6

1

20

High-throughput

0.536

High

633271

YD17A
Transposon Ty1-DR2 Gag polyprotein

1

1

High-throughput

0.536

High

633261

SKP2
F-box protein SKP2

1

0

Small-scale

0.527

High

633246

DUT
Deoxyuridine 5'-triphosphate nucleotidohydrolase

1

0

High-throughput

0.518

High

518200

IF4A
ATP-dependent RNA helicase eIF4A

1

1

High-throughput

0.515

High

633232

IF5A1
Eukaryotic translation initiation factor 5A-1

1

0

High-throughput

0.513

High

633269

YE11B
Transposon Ty1-ER1 Gag-Pol polyprotein

1

0

High-throughput

0.513

High

633273

BUR2
Protein BUR2

1

0

High-throughput

0.513

High

633275

DIA2
Protein DIA2

1

0

High-throughput

0.513

High

633247

BMH2
Protein BMH2

1

0

High-throughput

0.493

High

633249

AHP1
Peroxiredoxin AHP1

1

0

High-throughput

0.493

High

633268

COFI
Cofilin

1

0

High-throughput

0.493

High

633259

ULP2
Ubiquitin-like-specific protease 2

1

1

High-throughput

0.481

High

633267

ULP1
Ubiquitin-like-specific protease 1

1

1

High-throughput

0.481

High

633237

HCM1
Forkhead transcription factor HCM1

1

0

Small-scale

0.480

High

633245

PRS7
26S proteasome regulatory subunit 7 homolog

1

0

Small-scale

0.480

High

486754

CDC16
Anaphase-promoting complex subunit CDC16

1

3

Small-scale

0.479

High

597597

CDC23
Anaphase-promoting complex subunit CDC23

1

3

Small-scale

0.479

High

633250

CDC27
Anaphase-promoting complex subunit CDC27

1

2

Small-scale

0.479

High

633253

KOG1
Target of rapamycin complex 1 subunit KOG1

1

0

High-throughput

0.460

High

381866

H4
Histone H4

1

0

Small-scale

0.458

High

633231

PSA7
Probable proteasome subunit alpha type-7

1

0

Small-scale

0.458

High

633239

PSB7
Proteasome subunit beta type-7

1

0

Small-scale

0.458

High

633240

SWC3
SWR1-complex protein 3

1

0

Small-scale

0.458

High

633244

PRS6B
26S proteasome regulatory subunit 6B homolog

1

0

Small-scale

0.458

High

633257

GLE2
mRNA export factor GLE2

1

0

Small-scale

0.458

High

633260

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

633263

SGF73
SAGA complex subunit SGF73

1

0

Small-scale

0.458

High

633264

AF9
Protein AF-9 homolog

1

0

Small-scale

0.458

High

633270

GIS1
Transcriptional activator/repressor GIS1

1

0

High-throughput

0.458

High

633272

SWR1
Helicase SWR1

1

0

Small-scale

0.458

High

633277

ARP6
Actin-like protein ARP6

1

0

Small-scale

0.458

High

633278

SUS1
SAGA complex subunit SUS1

1

0

Small-scale

0.458

High

392213

HSP82
ATP-dependent molecular chaperone HSP82

1

3

High-throughput

0.445

High

523035

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

543791

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

578831

HSC82
ATP-dependent molecular chaperone HSC82

1

3

High-throughput

0.445

High

633241

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

633254

SHU2
Suppressor of hydroxyurea sensitivity protein 2

1

0

High-throughput

0.438

High

633251

ATU1
P-type cation-transporting ATPase

2

0

High-throughput

0.307

High

633255

UIP3
ULP1-interacting protein 3

2

0

Small-scale

0.295

High

633256

RPN3
26S proteasome regulatory subunit RPN3

1

0

Small-scale

0.261

Low

633274

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

0

High-throughput

0.261

Low

512816

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.251

Low

633265

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.238

Low

633276

JID1
J domain-containing protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025