Interactor 1: EGFL7 (Q9UHF1)
Epidermal growth factor-like protein 7 (EGF-like protein 7) (Multiple epidermal growth factor-like domains protein 7) (Multiple EGF-like domains protein 7) (NOTCH4-like protein) (Vascular endothelial statin) (VE-statin) (Zneu1)
Gene: EGFL7

Interactor 2: NOTC3 (Q9UM47)
Neurogenic locus notch homolog protein 3 (Notch 3) [Cleaved into: Notch 3 extracellular truncation; Notch 3 intracellular domain]
Gene: NOTCH3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.55 1.00 0.744

The method score is based on:

Property Details
Experiments 19503073, unassigned3799
Identification Methods two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains EGF~FXa_inhibition, EGF_CA~FXa_inhibition
Common GO terms GO:0005509 - calcium ion binding
GO:0005576 - extracellular region
GO:0009986 - cell surface
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 273
Hs

1 2321
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Last updated: 11Aug2025