Interactor 1: PROS (P07225)
Vitamin K-dependent protein S
Gene: PROS1
Interactor 2: NOTC2 (Q04721)
Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)]
Gene: NOTCH2
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.33 | 1.00 | 0.575 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | unassigned3799 |
| Identification Methods | anti tag coimmunoprecipitation |
| Interaction Type | association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | EGF~EGF_CA, EGF_CA~EGF_CA, EGF_CA~hEGF, EGF~FXa_inhibition, EGF_CA~FXa_inhibition, EGF~Gla, EGF~hEGF, EGF~Laminin_G_2 |
| Common GO terms | GO:0000139 - Golgi membrane GO:0005509 - calcium ion binding GO:0005576 - extracellular region GO:0005789 - endoplasmic reticulum membrane GO:0005886 - plasma membrane |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
