HitPredict

Interactor 1: DRB1 (O04492)
Double-stranded RNA-binding protein 1 (Protein HYPONASTIC LEAVES 1) (dsRNA-binding protein 1) (AtDRB1)
Gene: DRB1

Interactor 2: DCL2 (Q3EBC8)
Endoribonuclease Dicer homolog 2 (EC 3.1.26.-) (Dicer-like protein 2) (AtDCL2)
Gene: At3g03300

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	15821876
Identification Methods	far western blotting
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Helicase_C~dsrm, PAZ~dsrm, Ribonuclease_3~dsrm
Common GO terms	GO:0005634 - nucleus GO:0010267 - ta-siRNA processing
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 419 At			1 1388
+	At
		146793 DRB1_ARATH (1-419): 2e-169: 482: 100.00		DCL1_ARATH (5-1372): 0: 934: 29.33
+	At
		146787 DRB1_ARATH (1-419): 2e-169: 482: 100.00		DCL3_ARATH (26-1384): 0: 802: 27.30
+	At
		1017394 DRB4_ARATH (14-262): 2.65e-53: 183: 28.11		DCL4_ARATH (10-1383): 0: 901: 31.76
+	Dm
		57216 Q9VLW8_DROME (13-293): 3.34e-56: 189: 17.18		DCR2_DROME (639-1384): 2.69e-98: 350: 18.86
+	Hs
		346171 STAU1_HUMAN (13-225): 7.71e-47: 171: 17.72		DHX58_HUMAN (23-526): 4.01e-100: 337: 21.71
+	Hs
		624113 E2AK2_HUMAN (7-218): 1.31e-43: 162: 19.73		DHX58_HUMAN (23-526): 4.01e-100: 337: 21.71
+	Hs
		937354 DSRAD_HUMAN (2-213): 6.09e-43: 163: 16.94		RNC_HUMAN (993-1381): 9.78e-88: 315: 19.05
+	Hs
		345728 STAU1_HUMAN (13-225): 7.71e-47: 171: 17.72		CHD3_HUMAN (10-774): 2.31e-77: 285: 13.35
+	Hs
		937302 DSRAD_HUMAN (2-213): 6.09e-43: 163: 16.94		CHD5_HUMAN (23-774): 1.89e-79: 292: 13.33
+	Hs
		345831 STAU1_HUMAN (13-225): 7.71e-47: 171: 17.72		CHD4_HUMAN (23-774): 9.91e-77: 283: 12.67
+	Hs
		937229 DSRAD_HUMAN (2-213): 6.09e-43: 163: 16.94		CHD3_HUMAN (10-774): 2.31e-77: 285: 13.35
+	Hs
		937250 DSRAD_HUMAN (2-213): 6.09e-43: 163: 16.94		CHD4_HUMAN (23-774): 9.91e-77: 283: 12.67
+	Hs
		287123 PRKRA_HUMAN (3-201): 6.09e-54: 183: 18.27		IFIH1_HUMAN (2-571): 5.4e-68: 251: 20.29
+	Hs
		286842 PRKRA_HUMAN (3-201): 6.09e-54: 183: 18.27		RIGI_HUMAN (9-571): 4.92e-68: 250: 21.51
+	Hs
		345042 E2AK2_HUMAN (7-218): 1.31e-43: 162: 19.73		RIGI_HUMAN (9-571): 4.92e-68: 250: 21.51
+	Hs
		345343 STAU1_HUMAN (13-225): 7.71e-47: 171: 17.72		DDX5_HUMAN (1-306): 3.22e-43: 170: 11.50
+	Hs
		346142 STAU1_HUMAN (13-225): 7.71e-47: 171: 17.72		DDX17_HUMAN (3-295): 5.79e-43: 170: 12.00
+	Hs
		287196 PRKRA_HUMAN (3-201): 6.09e-54: 183: 18.27		DICER_HUMAN (1035-1237): 3.77e-16: 86.9: 20.29
+	Hs
		346512 STAU1_HUMAN (13-225): 7.71e-47: 171: 17.72		DICER_HUMAN (1035-1237): 3.77e-16: 86.9: 20.29
+	Hs
		937373 DSRAD_HUMAN (2-213): 6.09e-43: 163: 16.94		DICER_HUMAN (1035-1237): 3.77e-16: 86.9: 20.29