HitPredict

Interactor 1: SMBT (Q9VK33)
Polycomb protein Sfmbt (Scm-like with four MBT domain-containing protein 1) (dSfmbt)
Gene: Sfmbt

Interactor 2: Q9W396 (Q9W396)
FI06908p (FI07108p) (Heterochromatin protein 1b, isoform A) (Heterochromatin protein 1b, isoform B) (Heterochromatin protein 1b, isoform C)
Gene: HP1b

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24186981
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0031507 - heterochromatin formation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1220 Dm			1 240
+	Mm
		947436 LMBL2_MOUSE (535-1055): 0: 625: 43.86		CBX5_MOUSE (4-165): 8e-69: 211: 47.02
+	Mm
		947460 LMBL2_MOUSE (535-1055): 0: 625: 43.86		Q9DCC5_MOUSE (3-159): 1.25e-67: 208: 52.87
+	Hs
		1097467 LMBL2_HUMAN (535-1058): 0: 623: 43.53		CBX3_HUMAN (3-159): 1.25e-67: 208: 52.87
+	Mm
		947425 LMBL2_MOUSE (535-1055): 0: 625: 43.86		CBX1_MOUSE (10-167): 2.27e-65: 202: 50.94
+	Hs
		1014175 LMBL2_HUMAN (535-1058): 0: 623: 43.53		CBX1_HUMAN (10-167): 2.27e-65: 202: 50.94
+	Hs
		1097636 SCML2_HUMAN (518-1202): 0: 579: 18.43		CBX3_HUMAN (3-159): 1.25e-67: 208: 52.87
+	Hs
		216506 LMBL2_HUMAN (535-1058): 0: 623: 43.53		SUV91_HUMAN (1-103): 1.02e-31: 121: 30.10
+	Hs
		339011 SCML2_HUMAN (518-1202): 0: 579: 18.43		CBX6_HUMAN (4-102): 3.27e-29: 115: 23.23
+	Hs
		129830 SCML2_HUMAN (518-1202): 0: 579: 18.43		CBX4_HUMAN (4-103): 4.14e-28: 113: 26.72
+	Hs
		1438671 SCML2_HUMAN (518-1202): 0: 579: 18.43		CBX8_HUMAN (4-94): 4.65e-26: 106: 27.47
+	Hs
		1132248 SCML2_HUMAN (518-1202): 0: 579: 18.43		CBX2_HUMAN (4-93): 1.01e-22: 97.8: 24.44
+	Mm
		1225157 PHC1_MOUSE (955-1202): 4.96e-53: 204: 20.76		CBX7_MOUSE (4-86): 1.35e-30: 112: 26.51
+	Hs
		338809 PHC1_HUMAN (955-1202): 7.37e-51: 197: 20.38		CBX6_HUMAN (4-102): 3.27e-29: 115: 23.23
+	Hs
		351380 PHC1_HUMAN (955-1202): 7.37e-51: 197: 20.38		CBX7_HUMAN (4-93): 1.29e-30: 115: 26.67
+	Hs
		72733 PHC1_HUMAN (955-1202): 7.37e-51: 197: 20.38		B0QXZ6_HUMAN (4-97): 4.84e-29: 114: 24.47
+	Hs
		129713 PHC1_HUMAN (955-1202): 7.37e-51: 197: 20.38		CBX4_HUMAN (4-103): 4.14e-28: 113: 26.72
+	Hs
		1006879 PHC1_HUMAN (955-1202): 7.37e-51: 197: 20.38		CBX8_HUMAN (4-94): 4.65e-26: 106: 27.47
+	Hs
		1006845 PHC1_HUMAN (955-1202): 7.37e-51: 197: 20.38		CBX2_HUMAN (4-93): 1.01e-22: 97.8: 24.44
+	Hs
		216483 PHC2_HUMAN (970-1201): 1.74e-43: 173: 17.62		SUV91_HUMAN (1-103): 1.02e-31: 121: 30.10
+	Hs
		129763 PHC2_HUMAN (970-1201): 1.74e-43: 173: 17.62		CBX4_HUMAN (4-103): 4.14e-28: 113: 26.72