HitPredict

Interactor 1: TR10B (O14763)
Tumor necrosis factor receptor superfamily member 10B (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD antigen CD262)
Gene: TNFRSF10B

Interactor 2: NFIP1 (Q9BT67)
NEDD4 family-interacting protein 1 (Breast cancer-associated protein SGA-1M) (NEDD4 WW domain-binding protein 5) (Putative MAPK-activating protein PM13) (Putative NF-kappa-B-activating protein 164) (Putative NFKB and MAPK-activating protein)
Gene: NDFIP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 221
+	Hs
		121529 TR10A_HUMAN (5-440): 4.6e-108: 329: 50.00		NFIP1_HUMAN (1-221): 1.9e-136: 383: 100.00
+	Hs
		1311869 EDAR_HUMAN (42-327): 3.58e-34: 134: 12.75		NFIP1_HUMAN (1-221): 1.9e-136: 383: 100.00
+	Hs
		1346376 EDAR_HUMAN (42-327): 3.58e-34: 134: 12.75		NFIP2_HUMAN (12-220): 5.72e-98: 290: 55.46