HitPredict

Interactor 1: SOCS2 (O14508)
Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2) (CIS-2) (STAT-induced STAT inhibitor 2) (SSI-2)
Gene: SOCS2

Interactor 2: PELP1 (Q8IZL8)
Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of non-genomic activity of estrogen receptor) (Transcription factor HMX3)
Gene: PELP1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24752897
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 198 Hs			1 1130
+	Hs
		557379 SRC_HUMAN (1-175): 6.33e-41: 146: 15.85		PELP1_HUMAN (1-1130): 0: 784: 100.00
+	Rn
		1201238 SRC_RAT (1-175): 4.42e-41: 147: 15.85		PELP1_RAT (1-1130): 0: 661: 81.44
+	Hs
		473455 HCK_HUMAN (14-172): 1.31e-41: 148: 14.97		CBP_HUMAN (631-1010): 2.06e-28: 126: 16.87
+	Hs
		557412 SRC_HUMAN (1-175): 6.33e-41: 146: 15.85		CBP_HUMAN (631-1010): 2.06e-28: 126: 16.87
+	Hs
		463690 LYN_HUMAN (1-172): 1.29e-39: 142: 14.53		CBP_HUMAN (631-1010): 2.06e-28: 126: 16.87
+	Hs
		362149 ABL1_HUMAN (3-174): 1.28e-40: 148: 19.54		MUC1_HUMAN (443-1015): 7.05e-23: 108: 11.69
+	Hs
		439935 LCK_HUMAN (1-172): 2.86e-41: 147: 15.63		MUC1_HUMAN (443-1015): 7.05e-23: 108: 11.69
+	Hs
		440177 LCK_HUMAN (1-172): 2.86e-41: 147: 15.63		ASPP1_HUMAN (617-1076): 8.13e-23: 107: 15.50
+	Hs
		557066 SRC_HUMAN (1-175): 6.33e-41: 146: 15.85		MUC1_HUMAN (443-1015): 7.05e-23: 108: 11.69
+	Hs
		463316 LYN_HUMAN (1-172): 1.29e-39: 142: 14.53		MUC1_HUMAN (443-1015): 7.05e-23: 108: 11.69
+	Hs
		463708 LYN_HUMAN (1-172): 1.29e-39: 142: 14.53		ASPP1_HUMAN (617-1076): 8.13e-23: 107: 15.50
+	Hs
		440773 FYN_HUMAN (1-172): 1.04e-44: 157: 14.44		MAGL2_HUMAN (500-1038): 2.12e-09: 63.9: 10.31
+	Hs
		440048 LCK_HUMAN (1-172): 2.86e-41: 147: 15.63		EP300_HUMAN (697-1119): 6.36e-12: 72.7: 11.21
+	Hs
		557261 SRC_HUMAN (1-175): 6.33e-41: 146: 15.85		EP300_HUMAN (697-1119): 6.36e-12: 72.7: 11.21
+	Hs
		215893 LCK_HUMAN (1-172): 2.86e-41: 147: 15.63		SYNJ1_HUMAN (574-1003): 2.72e-11: 70.4: 16.12
+	Hs
		319045 LYN_HUMAN (1-172): 1.29e-39: 142: 14.53		K0754_HUMAN (441-729): 1.03e-11: 72: 14.88
+	Hs
		66953 SRC_HUMAN (1-175): 6.33e-41: 146: 15.85		L37A2_HUMAN (703-1130): 9.37e-09: 62: 14.95
+	Mm
		107051 LYN_MOUSE (1-172): 1.5e-39: 142: 14.53		F8VPR5_MOUSE (483-916): 5.8e-09: 62.8: 11.49
+	Hs
		699722 P85A_HUMAN (19-161): 1.34e-14: 73.2: 18.18		EP300_HUMAN (697-1119): 6.36e-12: 72.7: 11.21
+	Hs
		699836 P85A_HUMAN (19-161): 1.34e-14: 73.2: 18.18		MINT_HUMAN (731-1119): 5.58e-11: 69.6: 12.21