HitPredict

Interactor 1: KMT2D (O14686)
Histone-lysine N-methyltransferase 2D (Lysine N-methyltransferase 2D) (EC 2.1.1.364) (ALL1-related protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 2)
Gene: KMT2D

Interactor 2: FEV (Q99581)
Protein FEV (Fifth Ewing variant protein) (PC12 ETS domain-containing transcription factor 1) (PC12 ETS factor 1) (Pet-1)
Gene: FEV

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 5537 Hs			1 238
+	Hs
		161401 KMT2D_HUMAN (1-5537): 0: 1919: 100.00		ERG_HUMAN (3-237): 3.12e-67: 216: 46.86
+	Hs
		161403 KMT2D_HUMAN (1-5537): 0: 1919: 100.00		ETS1_HUMAN (8-151): 3.56e-55: 184: 46.31
+	Hs
		161505 KMT2D_HUMAN (1-5537): 0: 1919: 100.00		ELF4_HUMAN (2-217): 1.34e-48: 170: 26.61
+	Hs
		161428 KMT2D_HUMAN (1-5537): 0: 1919: 100.00		ETV4_HUMAN (36-186): 7.65e-47: 163: 39.74
+	Hs
		161425 KMT2D_HUMAN (1-5537): 0: 1919: 100.00		ETV5_HUMAN (20-170): 1.6e-42: 152: 39.47
+	Hs
		1405437 EHMT1_HUMAN (4886-5533): 5.22e-112: 394: 15.17		FEV_HUMAN (1-238): 3.34e-94: 277: 100.00
+	Hs
		1396287 EHMT2_HUMAN (4886-5533): 3.82e-112: 392: 17.77		FEV_HUMAN (1-238): 3.34e-94: 277: 100.00
+	Hs
		1152745 EHMT1_HUMAN (4886-5533): 5.22e-112: 394: 15.17		ELF2_HUMAN (6-234): 1.22e-48: 170: 24.58
+	Hs
		832578 EHMT1_HUMAN (4886-5533): 5.22e-112: 394: 15.17		ETV3_HUMAN (30-193): 6.5e-49: 169: 39.39
+	Hs
		1152727 EHMT2_HUMAN (4886-5533): 3.82e-112: 392: 17.77		ELF2_HUMAN (6-234): 1.22e-48: 170: 24.58
+	Hs
		1396288 EHMT2_HUMAN (4886-5533): 3.82e-112: 392: 17.77		ELF4_HUMAN (2-217): 1.34e-48: 170: 26.61
+	Hs
		832560 EHMT2_HUMAN (4886-5533): 3.82e-112: 392: 17.77		ETV3_HUMAN (30-193): 6.5e-49: 169: 39.39
+	Hs
		837091 EHMT1_HUMAN (4886-5533): 5.22e-112: 394: 15.17		ELK3_HUMAN (61-215): 3.66e-42: 149: 29.68
+	Hs
		837078 EHMT2_HUMAN (4886-5533): 3.82e-112: 392: 17.77		ELK3_HUMAN (61-215): 3.66e-42: 149: 29.68
+	Hs
		540878 EZH2_HUMAN (5194-5519): 6.58e-90: 314: 18.91		ERG_HUMAN (3-237): 3.12e-67: 216: 46.86
+	Hs
		1041586 KMT2A_HUMAN (218-352): 4.01e-30: 135: 26.24		FEV_HUMAN (1-238): 3.34e-94: 277: 100.00
+	Hs
		738969 KMT2A_HUMAN (218-352): 4.01e-30: 135: 26.24		ELF1_HUMAN (4-230): 1.43e-59: 199: 23.61
+	Hs
		739045 KMT2B_HUMAN (79-219): 7.15e-25: 118: 24.31		ELF1_HUMAN (4-230): 1.43e-59: 199: 23.61
+	Hs
		1041535 KMT2A_HUMAN (218-352): 4.01e-30: 135: 26.24		ELF2_HUMAN (6-234): 1.22e-48: 170: 24.58
+	Hs
		837107 KMT2B_HUMAN (79-219): 7.15e-25: 118: 24.31		ELK3_HUMAN (61-215): 3.66e-42: 149: 29.68