HitPredict

Interactor 1: NRP1 (O14786)
Neuropilin-1 (Vascular endothelial cell growth factor 165 receptor) (CD antigen CD304)
Gene: NRP1

Interactor 2: TM11B (Q86T26)
Transmembrane protease serine 11B (EC 3.4.21.-) (Airway trypsin-like protease 5)
Gene: TMPRSS11B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	CUB~Trypsin, MAM~Trypsin
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 923 Hs			1 416
+	Hs
		164220 NRP1_HUMAN (1-923): 0: 1038: 100.00		HEPS_HUMAN (157-415): 9.91e-105: 318: 37.27
+	Hs
		249059 NRP2_HUMAN (5-923): 0: 885: 43.70		TMPSD_HUMAN (124-416): 7.87e-102: 316: 31.67
+	Hs
		249070 NRP2_HUMAN (5-923): 0: 885: 43.70		ST14_HUMAN (95-416): 3.96e-99: 316: 30.63
+	Hs
		1286874 DCBD2_HUMAN (142-585): 4.27e-69: 247: 23.58		TM11B_HUMAN (1-416): 0: 513: 100.00
+	Hs
		1399563 DCBD2_HUMAN (142-585): 4.27e-69: 247: 23.58		TMPSD_HUMAN (124-416): 7.87e-102: 316: 31.67
+	Hs
		944924 NETO2_HUMAN (25-307): 1.04e-68: 240: 20.53		TMPS3_HUMAN (158-414): 8.06e-106: 321: 38.08
+	Hs
		1335230 NETO2_HUMAN (25-307): 1.04e-68: 240: 20.53		ST14_HUMAN (95-416): 3.96e-99: 316: 30.63
+	Hs
		125806 MASP2_HUMAN (4-159): 5.42e-26: 116: 21.38		MASP1_HUMAN (40-416): 1.37e-112: 346: 24.50
+	Hs
		125795 MASP2_HUMAN (4-159): 5.42e-26: 116: 21.38		MASP2_HUMAN (37-414): 1.21e-109: 339: 22.51
+	Hs
		366350 PCOC1_HUMAN (147-375): 1.55e-34: 139: 22.71		PLMN_HUMAN (108-414): 3.73e-99: 314: 27.76
+	Hs
		437666 MFGM_HUMAN (428-614): 3.3e-32: 131: 29.02		HEPS_HUMAN (157-415): 9.91e-105: 318: 37.27
+	Hs
		1064073 MFGM_HUMAN (428-614): 3.3e-32: 131: 29.02		TMPSD_HUMAN (124-416): 7.87e-102: 316: 31.67
+	Hs
		1064086 MFGM_HUMAN (428-614): 3.3e-32: 131: 29.02		ST14_HUMAN (95-416): 3.96e-99: 316: 30.63
+	Hs
		437825 PCOC2_HUMAN (11-146): 6.9e-31: 128: 32.37		HEPS_HUMAN (157-415): 9.91e-105: 318: 37.27
+	Hs
		1418363 PCOC2_HUMAN (11-146): 6.9e-31: 128: 32.37		TMPSD_HUMAN (124-416): 7.87e-102: 316: 31.67
+	Hs
		1461337 PCOC2_HUMAN (11-146): 6.9e-31: 128: 32.37		ST14_HUMAN (95-416): 3.96e-99: 316: 30.63
+	Hs
		1064080 MFGM_HUMAN (428-614): 3.3e-32: 131: 29.02		TMPS4_HUMAN (156-413): 4.43e-101: 309: 36.68
+	Hs
		366116 C1R_HUMAN (9-141): 6.1e-25: 113: 24.09		C1R_HUMAN (65-414): 1.11e-102: 321: 22.40
+	Hs
		1491782 TLL2_HUMAN (5-140): 2.51e-24: 112: 27.34		ST14_HUMAN (95-416): 3.96e-99: 316: 30.63
+	Hs
		458003 BMP1_HUMAN (3-140): 3.33e-25: 114: 27.66		TRY2_HUMAN (184-414): 1.26e-98: 296: 35.35