Interactor 1: PER2 (O15055)
Period circadian protein homolog 2 (hPER2) (Circadian clock protein PERIOD 2)
Gene: PER2

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 0.60 0.711

The method score is based on:

Property Details
Experiments 26091241, 30425162, 34257372, 33961781, 17463251
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0042752 - regulation of circadian rhythm
GO:0045892 - negative regulation of DNA-templated transcription
and 1 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1255
Hs

1 605
+ Mm
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+ Hs
+ Mm
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+ Hs
+ Hs
+ Dm
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+ Dm
+ Hs
+ Hs

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Last updated: 15 Jul 2024