HitPredict

Interactor 1: NPC1 (O15118)
NPC intracellular cholesterol transporter 1 (Niemann-Pick C1 protein)
Gene: NPC1

Interactor 2: RAB9A (P51151)
Ras-related protein Rab-9A
Gene: RAB9A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	33144569, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005764 - lysosome GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1278 Hs			1 201
+	Hs
		167869 NPC1_HUMAN (1-1278): 0: 1389: 100.00		RAB7A_HUMAN (2-200): 5.12e-86: 254: 50.24
+	Hs
		167893 NPC1_HUMAN (1-1278): 0: 1389: 100.00		RAB1A_HUMAN (2-201): 3.43e-79: 236: 32.68
+	Hs
		168029 NPC1_HUMAN (1-1278): 0: 1389: 100.00		RAB1B_HUMAN (2-201): 1.7e-77: 232: 32.02
+	Hs
		914058 PTC1_HUMAN (814-1253): 9.07e-93: 330: 24.26		RB11A_HUMAN (3-201): 3.4e-75: 227: 35.38
+	Hs
		844896 SCAP_HUMAN (325-818): 2.41e-75: 276: 21.26		RAB7A_HUMAN (2-200): 5.12e-86: 254: 50.24