HitPredict

Interactor 1: SET1A (O15047)
Histone-lysine N-methyltransferase SETD1A (EC 2.1.1.364) (Lysine N-methyltransferase 2F) (SET domain-containing protein 1A) (hSET1A) (Set1/Ash2 histone methyltransferase complex subunit SET1)
Gene: SETD1A

Interactor 2: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.765

The method score is based on:

Property Details
Experiments 23453808, 23870121, 27563068, 29474905, 31076518, 24981860, 17355966, 22665483, 26186194, 28514442, 27705803, 33022573, 33961781, 16253997, 33472061, 20305087, 22266653, 15960975, unassigned3799
Identification Methods pull down, affinity chromatography technology, unspecified method, x-ray crystallography, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0035097 - histone methyltransferase complex
GO:0042800 - histone H3K4 methyltransferase activity
GO:0048188 - Set1C/COMPASS complex
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1707
Hs

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Last updated: 11Aug2025