Interactor 1: BIRC5 (O15392)
Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor 4) (Apoptosis inhibitor survivin)
Gene: BIRC5

Interactor 2: AURKB (Q96GD4)
Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)
Gene: AURKB

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.766

The method score is based on:

Property Details
Experiments 11516652, 12419797, 23945651, 24571573, 17099693, 16291752, 29568061, 31586073, 32738097, 31315909, 19995937, 21554500, 18477699, 19357306, 20430883, 27332895, 17681274
Identification Methods two hybrid, pull down, affinity chromatography technology, proximity labelling technology, protein kinase assay, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000278 - mitotic cell cycle
GO:0000281 - mitotic cytokinesis
GO:0000776 - kinetochore
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 13 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 142
Hs

1 344
+ Hs
+ Hs
+ Xl
+ Hs
+ Hs
+ Ce
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024