HitPredict

Interactor 1: BIRC5 (O15392)
Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor 4) (Apoptosis inhibitor survivin)
Gene: BIRC5

Interactor 2: UBP35 (Q9P2H5)
Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.4.19.12) (Deubiquitinating enzyme 35) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35)
Gene: USP35

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34438346
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 142 Hs			1 1018
+	Hs
		1036163 BIRC3_HUMAN (3-96): 8.83e-22: 91.7: 27.66		UBP35_HUMAN (1-1018): 0: 1039: 100.00
+	Hs
		177700 BIRC5_HUMAN (1-142): 2.27e-60: 184: 100.00		UBP38_HUMAN (1-993): 0: 884: 38.73
+	Hs
		177733 BIRC5_HUMAN (1-142): 2.27e-60: 184: 100.00		UBP22_HUMAN (622-926): 7.16e-41: 160: 15.12
+	Dm
		1176741 Q9VEM2_DROME (13-130): 5.9e-48: 153: 39.83		Q7JQI1_DROME (601-999): 1.53e-45: 179: 21.78
+	Hs
		777082 BIRC6_HUMAN (8-88): 8.14e-36: 132: 37.04		UBP8_HUMAN (660-932): 4.52e-38: 156: 21.22
+	Hs
		271165 BIRC7_HUMAN (7-104): 1.33e-33: 121: 29.59		UBP2_HUMAN (660-930): 5.02e-41: 162: 18.91
+	Dm
		1097052 DIAP1_DROME (8-89): 7.6e-22: 91.3: 26.83		Q7JQI1_DROME (601-999): 1.53e-45: 179: 21.78
+	Hs
		1035953 BIRC3_HUMAN (3-96): 8.83e-22: 91.7: 27.66		UBP7_HUMAN (750-997): 9.61e-30: 129: 22.22
+	Hs
		1036312 BIRC2_HUMAN (10-88): 1.01e-18: 82.9: 27.85		UBP7_HUMAN (750-997): 9.61e-30: 129: 22.22
+	Hs
		957751 XIAP_HUMAN (11-87): 7.51e-14: 69: 28.57		UBP7_HUMAN (750-997): 9.61e-30: 129: 22.22
+	Hs
		957762 XIAP_HUMAN (11-87): 7.51e-14: 69: 28.57		UBP47_HUMAN (686-983): 1.78e-26: 119: 17.86