HitPredict

Interactor 1: LSM1 (O15116)
U6 snRNA-associated Sm-like protein LSm1 (Cancer-associated Sm-like) (Small nuclear ribonuclear CaSm)
Gene: LSM1

Interactor 2: SMD2 (P62316)
Small nuclear ribonucleoprotein Sm D2 (Sm-D2) (snRNP core protein D2)
Gene: SNRPD2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0008380 - RNA splicing
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 133 Hs			1 118
+	Mm
		974306 LSM1_MOUSE (1-133): 1.13e-53: 166: 97.74		LSM3_MOUSE (13-109): 1.02e-33: 114: 26.80
+	Hs
		178011 LSM1_HUMAN (1-133): 3.58e-53: 165: 100.00		LSM3_HUMAN (13-109): 1.02e-33: 114: 26.80
+	Dm
		1477039 Q9W087_DROME (8-97): 1.71e-31: 109: 26.37		SMD2_DROME (3-114): 3.88e-41: 134: 89.29
+	Hs
		974690 LSM7_HUMAN (8-89): 4.36e-27: 98.5: 29.89		SMD2_HUMAN (1-118): 6.36e-44: 140: 100.00
+	Hs
		974520 RSMN_HUMAN (6-86): 1.44e-24: 95.8: 23.86		SMD2_HUMAN (1-118): 6.36e-44: 140: 100.00
+	Hs
		974109 RUXG_HUMAN (4-79): 1.76e-25: 93.5: 30.26		SMD2_HUMAN (1-118): 6.36e-44: 140: 100.00
+	Hs
		574206 RSMB_HUMAN (6-86): 1.43e-23: 93.1: 23.86		SMD2_HUMAN (1-118): 6.36e-44: 140: 100.00
+	Dm
		1303486 Q9W2K2_DROME (1-124): 3.54e-39: 130: 63.71		Q8IMX8_DROME (13-109): 2.16e-29: 103: 31.63
+	Dm
		1052576 RSMB_DROME (6-74): 5.13e-24: 93.1: 26.32		SMD2_DROME (3-114): 3.88e-41: 134: 89.29
+	Dm
		1477033 RUXG_DROME (4-79): 5.01e-25: 92.3: 30.26		SMD2_DROME (3-114): 3.88e-41: 134: 89.29
+	Hs
		344526 LSM8_HUMAN (7-95): 2.26e-31: 108: 33.33		LSM3_HUMAN (13-109): 1.02e-33: 114: 26.80
+	Mm
		974304 LSM8_MOUSE (7-95): 2.26e-31: 108: 33.33		LSM3_MOUSE (13-109): 1.02e-33: 114: 26.80
+	Hs
		974292 LSM7_HUMAN (8-89): 4.36e-27: 98.5: 29.89		LSM3_HUMAN (13-109): 1.02e-33: 114: 26.80
+	Dm
		1303485 Q9W087_DROME (8-97): 1.71e-31: 109: 26.37		Q8IMX8_DROME (13-109): 2.16e-29: 103: 31.63
+	Hs
		974106 RUXG_HUMAN (4-79): 1.76e-25: 93.5: 30.26		LSM3_HUMAN (13-109): 1.02e-33: 114: 26.80
+	Hs
		574203 RSMB_HUMAN (6-86): 1.43e-23: 93.1: 23.86		LSM3_HUMAN (13-109): 1.02e-33: 114: 26.80
+	Sc
		817165 RSMB_YEAST (7-118): 6.93e-23: 90.4: 22.14		SMD2_YEAST (3-114): 1.03e-33: 114: 52.68
+	Sc
		864124 LSM1_YEAST (4-123): 5.09e-34: 118: 40.98		LSM3_YEAST (26-109): 2.44e-20: 80.1: 27.38
+	Sp
		267758 LSM8_SCHPO (9-97): 6.23e-27: 97.7: 31.11		LSM3_SCHPO (19-109): 2.27e-27: 98.2: 30.77
+	Sc
		817142 RSMB_YEAST (7-118): 6.93e-23: 90.4: 22.14		LSM3_YEAST (26-109): 2.44e-20: 80.1: 27.38