HitPredict

Interactor 1: RPA34 (O15446)
DNA-directed RNA polymerase I subunit RPA34 (A34.5) (Antisense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (DNA-directed RNA polymerase I subunit G) (RNA polymerase I-associated factor PAF49)
Gene: POLR1G

Interactor 2: SMC1A (Q14683)
Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1-alpha) (SMC-1A) (Sb1.8)
Gene: SMC1A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005694 - chromosome GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 510 Hs			1 1233
+	Hs
		1057289 NIPBL_HUMAN (160-509): 1.23e-45: 174: 14.00		SMC1A_HUMAN (1-1233): 1.94e-128: 427: 100.00
+	Mm
		1154101 NIPBL_MOUSE (154-510): 5.54e-40: 157: 15.05		SMC1A_MOUSE (1-1233): 1.34e-128: 427: 99.84
+	Hs
		1057338 TITIN_HUMAN (60-509): 8.33e-09: 60.8: 10.21		SMC1A_HUMAN (1-1233): 1.94e-128: 427: 100.00
+	Hs
		1056828 MDC1_HUMAN (88-510): 8.73e-09: 60.4: 10.54		SMC1A_HUMAN (1-1233): 1.94e-128: 427: 100.00
+	Hs
		1154087 NIPBL_HUMAN (160-509): 1.23e-45: 174: 14.00		SMC3_HUMAN (3-1229): 1.52e-70: 260: 16.00
+	Mm
		1154102 NIPBL_MOUSE (154-510): 5.54e-40: 157: 15.05		SMC3_MOUSE (3-1229): 1.17e-70: 261: 16.00
+	Dm
		53909 A1Z987_DROME (24-444): 9.35e-09: 60.2: 13.10		Q7KK96_DROME (3-1217): 9.76e-94: 329: 18.00
+	Dm
		53910 A1Z987_DROME (24-444): 9.35e-09: 60.2: 13.10		Q9V3A7_DROME (4-1233): 4.02e-81: 294: 18.87