HitPredict

Interactor 1: ZFYV9 (O95405)
Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Novel serine protease) (NSP) (Receptor activation anchor) (hSARA) (Smad anchor for receptor activation)
Gene: ZFYVE9

Interactor 2: FGFR1 (P11362)
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1425 Hs			1 822
+	Hs
		336068 ZFYV9_HUMAN (1-1425): 0: 1619: 100.00		FGFR2_HUMAN (1-812): 0: 794: 71.50
+	Hs
		336069 ZFYV9_HUMAN (1-1425): 0: 1619: 100.00		FGFR4_HUMAN (31-813): 0: 660: 55.33
+	Hs
		336106 ZFYV9_HUMAN (1-1425): 0: 1619: 100.00		EPHA7_HUMAN (3-783): 0: 624: 19.40
+	Hs
		336084 ZFYV9_HUMAN (1-1425): 0: 1619: 100.00		EPHA4_HUMAN (3-783): 0: 615: 19.44
+	Hs
		336071 ZFYV9_HUMAN (1-1425): 0: 1619: 100.00		EPHA2_HUMAN (3-819): 0: 583: 18.48
+	Hs
		336108 ZFYV9_HUMAN (1-1425): 0: 1619: 100.00		NTRK2_HUMAN (102-762): 3.21e-162: 493: 22.70
+	Hs
		541566 ZFY16_HUMAN (1-1424): 0: 1145: 30.52		FGFR1_HUMAN (1-822): 0: 858: 100.00
+	Hs
		641203 ZFY16_HUMAN (1-1424): 0: 1145: 30.52		FGFR2_HUMAN (1-812): 0: 794: 71.50
+	Hs
		336052 ZFYV9_HUMAN (1-1425): 0: 1619: 100.00		CSF1R_HUMAN (212-750): 1.68e-79: 277: 32.28
+	Hs
		648568 ZFY16_HUMAN (1-1424): 0: 1145: 30.52		FGFR4_HUMAN (31-813): 0: 660: 55.33
+	Hs
		710854 ZFY16_HUMAN (1-1424): 0: 1145: 30.52		EPHB2_HUMAN (4-819): 0: 637: 18.07
+	Hs
		931862 ZFY16_HUMAN (1-1424): 0: 1145: 30.52		EPHA5_HUMAN (3-791): 0: 630: 18.90
+	Hs
		1147359 ZFY16_HUMAN (1-1424): 0: 1145: 30.52		EPHA7_HUMAN (3-783): 0: 624: 19.40
+	Hs
		932092 ZFY16_HUMAN (1-1424): 0: 1145: 30.52		EPHA4_HUMAN (3-783): 0: 615: 19.44
+	Hs
		641169 MTMR3_HUMAN (196-777): 1.1e-66: 249: 12.16		FGFR2_HUMAN (1-812): 0: 794: 71.50
+	Hs
		650169 EEA1_HUMAN (2-758): 1.25e-64: 244: 13.07		FGFR3_HUMAN (6-821): 0: 727: 61.22
+	Hs
		710653 RUFY1_HUMAN (156-763): 3.83e-101: 341: 14.56		EPHA3_HUMAN (3-775): 0: 627: 19.29
+	Hs
		412479 RUFY1_HUMAN (156-763): 3.83e-101: 341: 14.56		NTRK1_HUMAN (122-769): 1.36e-139: 434: 25.96
+	Hs
		412144 RUFY3_HUMAN (138-584): 9.87e-63: 224: 11.45		NTRK1_HUMAN (122-769): 1.36e-139: 434: 25.96
+	Hs
		773346 EEA1_HUMAN (2-758): 1.25e-64: 244: 13.07		TIE1_HUMAN (484-771): 2.12e-70: 253: 47.57