HitPredict

Interactor 1: ZFYV9 (O95405)
Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Novel serine protease) (NSP) (Receptor activation anchor) (hSARA) (Smad anchor for receptor activation)
Gene: ZFYVE9

Interactor 2: DDR2 (Q16832)
Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)
Gene: DDR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1425 Hs			1 855
+	Hs
		336108 ZFYV9_HUMAN (1-1425): 0: 1619: 100.00		NTRK2_HUMAN (498-850): 2.11e-106: 348: 40.50
+	Hs
		336056 ZFYV9_HUMAN (1-1425): 0: 1619: 100.00		FGFR1_HUMAN (505-851): 3.16e-102: 337: 32.49
+	Hs
		336068 ZFYV9_HUMAN (1-1425): 0: 1619: 100.00		FGFR2_HUMAN (522-851): 6.79e-102: 336: 34.42
+	Hs
		336069 ZFYV9_HUMAN (1-1425): 0: 1619: 100.00		FGFR4_HUMAN (537-849): 5.05e-98: 325: 34.78
+	Hs
		541566 ZFY16_HUMAN (1-1424): 0: 1145: 30.52		FGFR1_HUMAN (505-851): 3.16e-102: 337: 32.49
+	Hs
		641203 ZFY16_HUMAN (1-1424): 0: 1145: 30.52		FGFR2_HUMAN (522-851): 6.79e-102: 336: 34.42
+	Hs
		648568 ZFY16_HUMAN (1-1424): 0: 1145: 30.52		FGFR4_HUMAN (537-849): 5.05e-98: 325: 34.78
+	Hs
		412479 RUFY1_HUMAN (156-763): 3.83e-101: 341: 14.56		NTRK1_HUMAN (551-850): 4.93e-101: 333: 42.62
+	Hs
		641169 MTMR3_HUMAN (196-777): 1.1e-66: 249: 12.16		FGFR2_HUMAN (522-851): 6.79e-102: 336: 34.42
+	Hs
		650169 EEA1_HUMAN (2-758): 1.25e-64: 244: 13.07		FGFR3_HUMAN (485-851): 6.42e-101: 333: 31.28
+	Hs
		412144 RUFY3_HUMAN (138-584): 9.87e-63: 224: 11.45		NTRK1_HUMAN (551-850): 4.93e-101: 333: 42.62
+	Mm
		582011 HGS_MOUSE (654-976): 8.69e-53: 201: 19.94		NTRK2_MOUSE (498-850): 7.52e-107: 349: 40.50
+	Hs
		710653 RUFY1_HUMAN (156-763): 3.83e-101: 341: 14.56		EPHA3_HUMAN (554-845): 1.09e-54: 206: 38.93
+	Hs
		465554 FGD5_HUMAN (151-872): 5.83e-92: 329: 14.76		IGF1R_HUMAN (535-845): 9.38e-58: 217: 40.13
+	Hs
		169413 HGS_HUMAN (654-976): 1.2e-52: 201: 19.55		FGFR1_HUMAN (505-851): 3.16e-102: 337: 32.49
+	Hs
		169385 HGS_HUMAN (654-976): 1.2e-52: 201: 19.55		NTRK1_HUMAN (551-850): 4.93e-101: 333: 42.62
+	Hs
		465525 EEA1_HUMAN (2-758): 1.25e-64: 244: 13.07		IGF1R_HUMAN (535-845): 9.38e-58: 217: 40.13
+	Rn
		98809 F1LUA1_RAT (40-758): 7.32e-61: 232: 12.61		INSR_RAT (511-849): 4.36e-54: 206: 37.46
+	Rn
		93200 D4A1J6_RAT (222-760): 2.42e-54: 210: 12.68		INSR_RAT (511-849): 4.36e-54: 206: 37.46
+	Hs
		169391 HGS_HUMAN (654-976): 1.2e-52: 201: 19.55		INSR_HUMAN (511-849): 1.55e-55: 210: 37.76