HitPredict

Interactor 1: GPR42 (O15529)
G-protein coupled receptor 42
Gene: GPR42

Interactor 2: ZNT3 (Q99726)
Probable proton-coupled zinc antiporter SLC30A3 (Solute carrier family 30 member 3) (Zinc transporter 3) (ZnT-3)
Gene: SLC30A3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	unassigned1304
Identification Methods	two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 346 Hs			1 388
+	Hs
		193443 GPR42_HUMAN (1-346): 3.95e-79: 247: 100.00		ZNT2_HUMAN (27-386): 1.29e-121: 358: 50.82
+	Hs
		770908 OPRM_HUMAN (5-334): 7.02e-72: 230: 20.18		ZNT2_HUMAN (27-386): 1.29e-121: 358: 50.82
+	Hs
		194740 FFAR2_HUMAN (16-314): 9.16e-69: 220: 42.53		ZNT2_HUMAN (27-386): 1.29e-121: 358: 50.82
+	Hs
		193426 GPR42_HUMAN (1-346): 3.95e-79: 247: 100.00		ZNT8_HUMAN (10-385): 7.34e-109: 325: 42.30
+	Hs
		1101597 GPR17_HUMAN (16-317): 6.9e-79: 247: 26.67		ZNT5_HUMAN (23-372): 7.62e-100: 314: 18.02
+	Hs
		907037 CCR6_HUMAN (13-334): 2.6e-78: 246: 20.77		ZNT5_HUMAN (23-372): 7.62e-100: 314: 18.02
+	Hs
		221462 OX2R_HUMAN (14-318): 1.1e-65: 215: 15.17		ZNT5_HUMAN (23-372): 7.62e-100: 314: 18.02
+	Hs
		1101593 GPR17_HUMAN (16-317): 6.9e-79: 247: 26.67		ZNT7_HUMAN (65-371): 7.9e-85: 264: 18.57
+	Hs
		956944 CXCR4_HUMAN (13-294): 8.36e-78: 244: 20.75		ZNT7_HUMAN (65-371): 7.9e-85: 264: 18.57
+	Hs
		1101531 GPR17_HUMAN (16-317): 6.9e-79: 247: 26.67		ZNT6_HUMAN (71-369): 3.27e-67: 221: 22.33
+	Hs
		833841 P2RY2_HUMAN (28-279): 9.6e-21: 94: 28.52		ZNT5_HUMAN (23-372): 7.62e-100: 314: 18.02
+	Hs
		1291843 P2RY8_HUMAN (20-291): 2.99e-30: 119: 31.49		ZNT7_HUMAN (65-371): 7.9e-85: 264: 18.57
+	Hs
		165994 FFAR1_HUMAN (18-250): 7.81e-26: 106: 36.36		ZNT7_HUMAN (65-371): 7.9e-85: 264: 18.57
+	Hs
		833840 P2RY2_HUMAN (28-279): 9.6e-21: 94: 28.52		ZNT7_HUMAN (65-371): 7.9e-85: 264: 18.57
+	Mm
		723378 SSR3_MOUSE (2-342): 4.67e-66: 216: 20.88		ZNT1_MOUSE (70-204): 3.86e-35: 136: 27.21
+	Hs
		1337950 P2Y12_HUMAN (20-325): 1.14e-16: 81.6: 22.29		ZNT7_HUMAN (65-371): 7.9e-85: 264: 18.57
+	Hs
		833828 P2RY2_HUMAN (28-279): 9.6e-21: 94: 28.52		ZNT6_HUMAN (71-369): 3.27e-67: 221: 22.33
+	Hs
		936072 PAR2_HUMAN (16-284): 1e-29: 119: 30.61		ZNT9_HUMAN (61-346): 2.78e-56: 195: 13.50
+	Hs
		1142087 P2RY6_HUMAN (20-298): 3.28e-21: 94.4: 27.09		ZNT9_HUMAN (61-346): 2.78e-56: 195: 13.50