Protein: P2Y12
P2Y purinoceptor 12 (P2Y12) (ADP-glucose receptor) (ADPG-R) (P2T(AC)) (P2Y(AC)) (P2Y(cyc)) (P2Y12 platelet ADP receptor) (P2Y(ADP)) (SP1999)

Gene: P2Y12, P2RY12
Organism: Homo sapiens
Interactions: 63
UniProt ID: Q9H244

Gene Ontology (top 5):
GO:0001609 - G protein-coupled adenosine receptor activity
GO:0001621 - G protein-coupled ADP receptor activity
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005886 - plasma membrane
GO:0006811 - monoatomic ion transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

349564

TSN15
Tetraspanin-15

3

20

High-throughput

0.667

High

443968

ATPB
ATP synthase F(1) complex subunit beta, mitochondrial

3

13

High-throughput

0.667

High

665707

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

3

7

High-throughput

0.667

High

1041276

CAV1
Caveolin-1

3

6

High-throughput

0.667

High

1128371

ITPR2
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2

3

4

High-throughput

0.667

High

1216914

TM164
Transmembrane protein 164

3

3

High-throughput

0.667

High

1251748

CERS6
Ceramide synthase 6

3

17

High-throughput

0.667

High

1254310

TMPPE
Transmembrane protein with metallophosphoesterase domain

3

2

High-throughput

0.667

High

1315481

K2013
Uncharacterized protein KIAA2013

3

9

High-throughput

0.667

High

1337027

T161B
Transmembrane protein 161B

3

7

High-throughput

0.667

High

1348317

GOGA5
Golgin subfamily A member 5

3

8

High-throughput

0.667

High

1358445

LMBR1
Limb region 1 protein homolog

3

4

High-throughput

0.667

High

1393079

CREL1
Protein disulfide isomerase CRELD1

3

5

High-throughput

0.667

High

1421250

TTYH3
Protein tweety homolog 3

3

6

High-throughput

0.667

High

1428151

YIPF3
Protein YIPF3

3

8

High-throughput

0.667

High

1431460

GOLP3
Golgi phosphoprotein 3

3

4

High-throughput

0.667

High

1431463

TM9S3
Transmembrane 9 superfamily member 3

2

12

High-throughput

0.628

High

1431459

P2Y12
P2Y purinoceptor 12

1

17

Small-scale

0.618

High

297266

PRAF3
PRA1 family protein 3

2

4

High-throughput

0.611

High

403223

APOB
Apolipoprotein B-100

2

2

High-throughput

0.611

High

536288

PPAL
Lysosomal acid phosphatase

2

2

High-throughput

0.611

High

1273968

DYM
Dymeclin

2

8

High-throughput

0.611

High

1431468

S39A1
Zinc transporter ZIP1

2

18

High-throughput

0.611

High

1142941

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

3

2

High-throughput

0.609

High

1210392

TT39A
Tetratricopeptide repeat protein 39A

3

1

High-throughput

0.609

High

1327503

CERS5
Ceramide synthase 5

3

17

High-throughput

0.609

High

1340565

MFSD8
Major facilitator superfamily domain-containing protein 8

3

10

High-throughput

0.609

High

1395625

RN170
E3 ubiquitin-protein ligase RNF170

3

2

High-throughput

0.609

High

1410311

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

3

2

High-throughput

0.609

High

1421100

XPO4
Exportin-4

3

20

High-throughput

0.609

High

1431462

MRS2
Magnesium transporter MRS2 homolog, mitochondrial

3

3

High-throughput

0.609

High

1431464

SAC1
Phosphatidylinositol-3-phosphatase SAC1

3

4

High-throughput

0.609

High

1431466

GEMI8
Gem-associated protein 8

3

1

High-throughput

0.609

High

1431470

CS025
UPF0449 protein C19orf25

3

4

High-throughput

0.609

High

1431473

TNPO3
Transportin-3

3

20

High-throughput

0.609

High

506661

GPHRB
Golgi pH regulator B

3

14

High-throughput

0.585

High

1329520

FITM2
Acyl-coenzyme A diphosphatase FITM2

2

2

High-throughput

0.574

High

360294

COX1
Cytochrome c oxidase subunit 1

2

3

High-throughput

0.558

High

397621

NU1M
NADH-ubiquinone oxidoreductase chain 1

2

2

High-throughput

0.558

High

1331250

ARL10
ADP-ribosylation factor-like protein 10

2

10

High-throughput

0.558

High

1360303

GEMI6
Gem-associated protein 6

2

2

High-throughput

0.558

High

1431461

ACAD9
Complex I assembly factor ACAD9, mitochondrial

2

10

High-throughput

0.558

High

923436

SC5A3
Sodium/myo-inositol cotransporter

2

3

High-throughput

0.552

High

1415273

PTSS2
Phosphatidylserine synthase 2

1

10

High-throughput

0.536

High

85402

GPHRA
Golgi pH regulator A

2

14

High-throughput

0.504

High

248243

NDK8
Putative nucleoside diphosphate kinase

2

1

High-throughput

0.504

High

298800

ATP5H
ATP synthase peripheral stalk subunit d, mitochondrial

1

4

High-throughput

0.489

High

609803

LEG3
Galectin-3

1

4

High-throughput

0.479

High

944560

GEMI4
Gem-associated protein 4

1

4

High-throughput

0.479

High

1431467

CKLF6
CKLF-like MARVEL transmembrane domain-containing protein 6

1

4

High-throughput

0.479

High

1431469

PALS2
Protein PALS2

1

15

High-throughput

0.479

High

1431471

DDX20
Probable ATP-dependent RNA helicase DDX20

1

2

High-throughput

0.479

High

1203429

AG10A
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase

1

8

High-throughput

0.437

High

1322211

VKORL
Vitamin K epoxide reductase complex subunit 1-like protein 1

1

5

High-throughput

0.437

High

1337950

ZNT7
Zinc transporter 7

1

13

High-throughput

0.437

High

1361359

BRI3B
BRI3-binding protein

1

2

High-throughput

0.437

High

1382719

RFT1
Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1

1

1

High-throughput

0.437

High

1389588

SAAL1
Protein SAAL1

1

3

High-throughput

0.437

High

1431465

RMND1
Required for meiotic nuclear division protein 1 homolog

1

3

High-throughput

0.437

High

1431472

IPO11
Importin-11

1

20

High-throughput

0.437

High

916198

BIEA
Biliverdin reductase A

2

0

High-throughput

0.328

High

1232853

PTRD1
Putative peptidyl-tRNA hydrolase PTRHD1

2

0

High-throughput

0.328

High


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Last updated: 11Aug2025