HitPredict

Interactor 1: KDM6A (O15550)
Lysine-specific demethylase 6A (EC 1.14.11.68) (Histone demethylase UTX) (Ubiquitously-transcribed TPR protein on the X chromosome) (Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein) ([histone H3]-trimethyl-L-lysine(27) demethylase 6A)
Gene: KDM6A

Interactor 2: PPARG (P37231)
Peroxisome proliferator-activated receptor gamma (PPAR-gamma) (Nuclear receptor subfamily 1 group C member 3)
Gene: PPARG

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1401 Hs			1 505
+	Hs
		194495 KDM6A_HUMAN (1-1401): 0: 1667: 100.00		GCR_HUMAN (18-503): 2e-98: 315: 17.85
+	Hs
		194519 KDM6A_HUMAN (1-1401): 0: 1667: 100.00		HNF4A_HUMAN (114-501): 4.64e-100: 311: 21.34
+	Hs
		194595 KDM6A_HUMAN (1-1401): 0: 1667: 100.00		ESR2_HUMAN (23-502): 1.8e-98: 308: 18.70
+	Hs
		158684 UTY_HUMAN (1-1393): 0: 1523: 83.49		GCR_HUMAN (18-503): 2e-98: 315: 17.85
+	Hs
		789559 DNJC7_HUMAN (278-509): 2.61e-21: 101: 11.16		PPARG_HUMAN (1-505): 2.48e-165: 479: 100.00
+	Hs
		520627 BBS4_HUMAN (62-568): 1.13e-53: 199: 12.70		RARA_HUMAN (45-503): 3.9e-102: 316: 25.22
+	Hs
		565534 BBS4_HUMAN (62-568): 1.13e-53: 199: 12.70		RARG_HUMAN (69-503): 8.3e-94: 294: 25.73
+	Dm
		120167 M9PCJ7_DROME (176-523): 2.28e-40: 164: 42.94		ECR_DROME (108-501): 2.19e-101: 325: 25.82
+	Hs
		185336 OGT1_HUMAN (255-640): 7.42e-29: 127: 10.91		ESR1_HUMAN (1-501): 9.13e-112: 345: 19.28
+	Hs
		396787 DNJC7_HUMAN (278-509): 2.61e-21: 101: 11.16		ESR1_HUMAN (1-501): 9.13e-112: 345: 19.28
+	Mm
		1222867 OGT1_MOUSE (255-640): 7.94e-29: 127: 10.91		ERR2_MOUSE (25-502): 1.45e-103: 318: 19.75
+	Hs
		176016 KDM6B_HUMAN (252-871): 4.19e-18: 93.1: 16.07		ESR1_HUMAN (1-501): 9.13e-112: 345: 19.28
+	Hs
		185892 OGT1_HUMAN (255-640): 7.42e-29: 127: 10.91		ESR2_HUMAN (23-502): 1.8e-98: 308: 18.70
+	Hs
		396346 CTR9_HUMAN (173-479): 5.74e-17: 89.3: 10.64		ESR1_HUMAN (1-501): 9.13e-112: 345: 19.28
+	Hs
		282949 DNJC7_HUMAN (278-509): 2.61e-21: 101: 11.16		NR1I2_HUMAN (139-501): 1.19e-104: 321: 26.26
+	Hs
		404369 DNJC7_HUMAN (278-509): 2.61e-21: 101: 11.16		GCR_HUMAN (18-503): 2e-98: 315: 17.85
+	Hs
		1367540 CDC23_HUMAN (89-333): 4.95e-23: 107: 16.60		ESR2_HUMAN (23-502): 1.8e-98: 308: 18.70
+	Hs
		652530 TMTC4_HUMAN (233-447): 1.54e-20: 100: 18.89		NR4A1_HUMAN (4-503): 3.34e-99: 312: 20.83
+	Mm
		1222823 CTR9_MOUSE (173-479): 9.95e-17: 88.5: 10.64		ERR2_MOUSE (25-502): 1.45e-103: 318: 19.75
+	Hs
		1243839 CTR9_HUMAN (173-479): 5.74e-17: 89.3: 10.64		ESR2_HUMAN (23-502): 1.8e-98: 308: 18.70