HitPredict

Interactor 1: PER1 (O35973)
Period circadian protein homolog 1 (mPER1) (Circadian clock protein PERIOD 1) (Circadian pacemaker protein Rigui)
Gene: PER1

Interactor 2: PER3 (O70361)
Period circadian protein homolog 3 (mPER3) (Circadian clock protein PERIOD 3)
Gene: PER3

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.55 1.00 0.743

The method score is based on:

Property Details
Experiments 14701732, 24737000
Identification Methods affinity chromatography technology, two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PAS_3~PAS_3, PAS_3~Per3-like_PAS-A, Per3-like_PAS-A~Per3-like_PAS-A
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0007623 - circadian rhythm
GO:0019900 - kinase binding
GO:0031625 - ubiquitin protein ligase binding
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1291
Mm

1 1113
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025