Interactor 1: MSH5 (O43196)
MutS protein homolog 5 (hMSH5)
Gene: MSH5
Interactor 2: MLH1 (P40692)
DNA mismatch repair protein Mlh1 (MutL protein homolog 1)
Gene: MLH1
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32814904 |
| Identification Methods | pull down |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | HATPase_c_3~MutS_III, HATPase_c_3~MutS_V |
| Common GO terms | GO:0005524 - ATP binding GO:0005634 - nucleus GO:0006298 - mismatch repair GO:0140664 - ATP-dependent DNA damage sensor activity |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
