HitPredict

Interactor 1: WIPF1 (O43516)
WAS/WASL-interacting protein family member 1 (Protein PRPL-2) (Wiskott-Aldrich syndrome protein-interacting protein) (WASP-interacting protein)
Gene: WIPF1

Interactor 2: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.91 0.60 0.739

The method score is based on:

Property Details
Experiments 28514442, 33961781, 20936779, 21706016, 21988832, unassigned3799
Identification Methods affinity chromatography technology, two hybrid, two hybrid array, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0017124 - SH3 domain binding
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 503
Hs

1 217
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025