HitPredict

Interactor 1: DUX1 (O43812)
Double homeobox protein 1
Gene: DUX1

Interactor 2: DESM (P17661)
Desmin
Gene: DES

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.42	0.60	0.506

Property	Details
Experiments	26816005
Identification Methods	two hybrid, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 170 Hs			1 470
+	Hs
		475046 DUX4_HUMAN (1-170): 3.9e-41: 144: 81.77		VIME_HUMAN (28-469): 1.75e-150: 438: 62.19
+	Hs
		437079 PO2F1_HUMAN (4-168): 9.82e-31: 118: 14.21		K2C8_HUMAN (81-464): 3.23e-139: 410: 35.01
+	Mm
		399477 PO5F1_MOUSE (9-168): 3.54e-29: 111: 15.00		GFAP_MOUSE (89-470): 1.16e-127: 379: 60.31
+	Hs
		606151 DUX5_HUMAN (1-170): 7.87e-44: 145: 100.00		DESM_HUMAN (1-470): 9.86e-110: 334: 100.00
+	Hs
		1200424 DUX4_HUMAN (1-170): 3.9e-41: 144: 81.77		Q53SB5_HUMAN (1-470): 9.86e-110: 334: 100.00
+	Hs
		606128 DUX4C_HUMAN (1-170): 1.05e-41: 144: 81.77		DESM_HUMAN (1-470): 9.86e-110: 334: 100.00
+	Hs
		606169 DUX4_HUMAN (1-170): 3.9e-41: 144: 81.77		DESM_HUMAN (1-470): 9.86e-110: 334: 100.00
+	Hs
		165153 PHX2A_HUMAN (20-79): 8.66e-15: 71.6: 45.00		PERI_HUMAN (12-470): 2.14e-134: 397: 59.14
+	Hs
		733128 OTX1_HUMAN (20-93): 8.11e-18: 80.9: 39.19		KRT81_HUMAN (1-416): 8.41e-96: 299: 30.95
+	Hs
		733120 OTX1_HUMAN (20-93): 8.11e-18: 80.9: 39.19		KRT83_HUMAN (9-423): 3.03e-95: 297: 30.55
+	Hs
		733121 OTX1_HUMAN (20-93): 8.11e-18: 80.9: 39.19		KRT85_HUMAN (1-416): 8.62e-91: 287: 29.93
+	Hs
		885243 HXA1_HUMAN (23-77): 1.8e-12: 65.7: 32.73		KRT81_HUMAN (1-416): 8.41e-96: 299: 30.95
+	Hs
		885215 HXA1_HUMAN (23-77): 1.8e-12: 65.7: 32.73		KRT83_HUMAN (9-423): 3.03e-95: 297: 30.55
+	Hs
		451103 HXB5_HUMAN (19-84): 9.18e-14: 68.8: 27.27		NFL_HUMAN (87-418): 9.8e-89: 282: 53.89
+	Hs
		277266 PITX3_HUMAN (6-86): 1.79e-19: 84.6: 29.63		K2C5_HUMAN (74-419): 2.75e-74: 246: 35.04
+	Hs
		277281 PITX3_HUMAN (6-86): 1.79e-19: 84.6: 29.63		K2C6C_HUMAN (9-435): 1.65e-74: 246: 30.02
+	Hs
		733191 OTX1_HUMAN (20-93): 8.11e-18: 80.9: 39.19		KRT35_HUMAN (19-422): 6.09e-75: 244: 28.50
+	Hs
		885354 HXA1_HUMAN (23-77): 1.8e-12: 65.7: 32.73		KRT35_HUMAN (19-422): 6.09e-75: 244: 28.50
+	Hs
		300633 OTX1_HUMAN (20-93): 8.11e-18: 80.9: 39.19		KRT37_HUMAN (5-432): 5.94e-69: 228: 28.31
+	Hs
		300637 HXA1_HUMAN (23-77): 1.8e-12: 65.7: 32.73		KRT37_HUMAN (5-432): 5.94e-69: 228: 28.31