HitPredict

Interactor 1: ITB3 (O54890)
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)
Gene: Itgb3

Interactor 2: FLNC (Q8VHX6)
Filamin-C (FLN-C) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin)
Gene: FLNC

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	30333137
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Filamin~Integrin_b_cyt
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 787 Mm			1 2726
+	Mm
		549408 ITB2_MOUSE (24-785): 0: 623: 38.45		FLNC_MOUSE (1-2726): 0: 2943: 100.00
+	Mm
		236612 ITB3_MOUSE (1-787): 0: 792: 100.00		FLNA_MOUSE (139-2726): 0: 1470: 35.18
+	Hs
		424010 ITB3_HUMAN (1-787): 0: 762: 90.61		FLNA_HUMAN (148-2726): 0: 1470: 35.39
+	Mm
		236605 ITB3_MOUSE (1-787): 0: 792: 100.00		FLNB_MOUSE (147-2726): 0: 1423: 35.29
+	Mm
		478537 ITB1_MOUSE (10-786): 0: 731: 43.27		FLNA_MOUSE (139-2726): 0: 1470: 35.18
+	Hs
		431706 ITB1_HUMAN (10-786): 0: 725: 43.52		FLNA_HUMAN (148-2726): 0: 1470: 35.39
+	Hs
		277992 ITB3_HUMAN (1-787): 0: 762: 90.61		FLNB_HUMAN (147-2726): 0: 1426: 35.51
+	Hs
		615312 ITB6_HUMAN (30-785): 0: 687: 49.87		FLNA_HUMAN (148-2726): 0: 1470: 35.39
+	Hs
		277994 ITB1_HUMAN (10-786): 0: 725: 43.52		FLNB_HUMAN (147-2726): 0: 1426: 35.51
+	Hs
		278009 ITB6_HUMAN (30-785): 0: 687: 49.87		FLNB_HUMAN (147-2726): 0: 1426: 35.51
+	Hs
		637353 ITB7_HUMAN (31-785): 0: 633: 38.56		FLNA_HUMAN (148-2726): 0: 1470: 35.39
+	Mm
		549398 ITB2_MOUSE (24-785): 0: 623: 38.45		FLNA_MOUSE (139-2726): 0: 1470: 35.18
+	Mm
		549394 ITB2_MOUSE (24-785): 0: 623: 38.45		FLNB_MOUSE (147-2726): 0: 1423: 35.29
+	Mm
		236590 ITB3_MOUSE (1-787): 0: 792: 100.00		SPTB2_MOUSE (4-440): 5.04e-117: 418: 24.72
+	Gg
		423974 ITB1_CHICK (8-786): 0: 727: 43.75		ACTN1_CHICK (7-438): 2.74e-119: 403: 24.61
+	Hs
		431675 ITB1_HUMAN (10-786): 0: 725: 43.52		ACTN1_HUMAN (6-438): 3.2e-119: 403: 24.56
+	Rn
		92874 ITB1_RAT (10-786): 0: 724: 43.09		D3ZCV0_RAT (21-435): 1.63e-117: 398: 25.12
+	Mm
		478504 ITB1_MOUSE (10-786): 0: 731: 43.27		ACTN4_MOUSE (33-359): 1.33e-101: 352: 28.02
+	Hs
		424070 ITB2_HUMAN (26-785): 0: 645: 38.73		SPTB2_HUMAN (4-440): 5.05e-117: 418: 24.72
+	Mm
		549386 ITB2_MOUSE (24-785): 0: 623: 38.45		SPTB2_MOUSE (4-440): 5.04e-117: 418: 24.72