HitPredict

Interactor 1: DNJA2 (O60884)
DnaJ homolog subfamily A member 2 (Cell cycle progression restoration gene 3 protein) (Dnj3) (Dj3) (HIRA-interacting protein 4) (Renal carcinoma antigen NY-REN-14)
Gene: DNAJA2

Interactor 2: DNJC7 (Q99615)
DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2)
Gene: DNAJC7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	1.00	0.802

Property	Details
Experiments	33957083, 35271311
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	DnaJ~DnaJ, DnaJ~DnaJ_C
Common GO terms	GO:0001671 - ATPase activator activity GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 412 Hs			1 494
+	Hs
		681574 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		DNJC7_HUMAN (1-494): 2.58e-85: 273: 100.00
+	Hs
		1262159 DNJA4_HUMAN (4-410): 3.01e-152: 437: 53.17		DNJC7_HUMAN (1-494): 2.58e-85: 273: 100.00
+	Hs
		1305132 DNJB4_HUMAN (6-358): 4.06e-118: 348: 33.05		DNJC7_HUMAN (1-494): 2.58e-85: 273: 100.00
+	Hs
		279337 DNJB5_HUMAN (6-356): 1.72e-114: 340: 32.42		DNJC7_HUMAN (1-494): 2.58e-85: 273: 100.00
+	Hs
		174480 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		OGT1_HUMAN (3-401): 1.62e-31: 130: 13.59
+	Hs
		243387 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		DNJC3_HUMAN (14-289): 8.21e-26: 112: 17.83
+	Hs
		243309 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Hs
		174656 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		OGT1_HUMAN (3-401): 1.62e-31: 130: 13.59
+	Sc
		542103 MAS5_YEAST (4-412): 6.79e-144: 417: 46.73		CYC8_YEAST (28-406): 2.74e-32: 133: 15.07
+	Hs
		1028085 DNJA4_HUMAN (4-410): 3.01e-152: 437: 53.17		DNJC3_HUMAN (14-289): 8.21e-26: 112: 17.83
+	Hs
		681339 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Hs
		681537 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		DNJB3_HUMAN (381-485): 1.24e-16: 78.6: 40.68
+	Dm
		247620 Q9VFV9_DROME (4-408): 3.25e-132: 387: 47.90		O61650_DROME (7-171): 4.01e-22: 101: 28.49
+	Ce
		183765 O16303_CAEEL (2-412): 5.53e-130: 382: 47.01		Q20774_CAEEL (380-489): 4.77e-21: 95.9: 46.83
+	Ce
		220083 O45502_CAEEL (4-411): 2.81e-128: 377: 45.97		Q20774_CAEEL (380-489): 4.77e-21: 95.9: 46.83
+	Hs
		279292 DNJB5_HUMAN (6-356): 1.72e-114: 340: 32.42		DNJC3_HUMAN (14-289): 8.21e-26: 112: 17.83
+	Hs
		685080 DNJB4_HUMAN (6-358): 4.06e-118: 348: 33.05		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Hs
		279279 DNJB5_HUMAN (6-356): 1.72e-114: 340: 32.42		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Hs
		279354 DNJB4_HUMAN (6-358): 4.06e-118: 348: 33.05		DNJB5_HUMAN (380-491): 5.82e-19: 90.1: 43.31