HitPredict

Interactor 1: TM1L1 (O75674)
TOM1-like protein 1 (Src-activating and signaling molecule protein) (Target of Myb-like protein 1)
Gene: TOM1L1

Interactor 2: CLH1 (Q00610)
Clathrin heavy chain 1 (Clathrin heavy chain on chromosome 17) (CLH-17)
Gene: CLTC

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.672

Property	Details
Experiments	16412388, 19798056, 17785434
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005764 - lysosome GO:0005768 - endosome GO:0005829 - cytosol GO:0016020 - membrane GO:0019901 - protein kinase binding and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 476 Hs			1 1675
+	Mm
		1148410 TM1L1_MOUSE (1-476): 2.94e-149: 435: 80.54		CLH1_MOUSE (1-1675): 0: 3131: 99.88
+	Hs
		960857 TM1L2_HUMAN (9-412): 1.02e-118: 359: 32.33		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		241163 TOM1_HUMAN (9-448): 1.15e-118: 358: 31.09		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		961012 GGA2_HUMAN (12-459): 1.57e-92: 294: 19.29		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		961013 GGA1_HUMAN (14-437): 9.61e-86: 278: 18.52		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		960999 GGA3_HUMAN (14-456): 1.88e-84: 276: 19.34		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		960908 STAM1_HUMAN (11-438): 3.47e-81: 263: 15.51		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Mm
		1148412 HGS_MOUSE (12-425): 7.55e-79: 262: 16.59		CLH1_MOUSE (1-1675): 0: 3131: 99.88
+	Hs
		159961 HGS_HUMAN (12-415): 8.76e-76: 254: 16.99		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		241158 TOM1_HUMAN (9-448): 1.15e-118: 358: 31.09		CLH2_HUMAN (1-1634): 0: 2869: 85.01
+	Hs
		863981 STAM1_HUMAN (11-438): 3.47e-81: 263: 15.51		CLH2_HUMAN (1-1634): 0: 2869: 85.01
+	Dm
		669650 Q9W329_DROME (15-399): 1.7e-53: 192: 16.21		CLH_DROME (1-1663): 0: 2911: 80.17
+	Dm
		669603 HRS_DROME (11-154): 1.52e-23: 106: 24.31		CLH_DROME (1-1663): 0: 2911: 80.17
+	Ce
		712329 Q17796_CAEEL (12-176): 3.58e-44: 167: 20.00		CLH_CAEEL (5-1671): 0: 2799: 71.19
+	Zm
		25357 C4J1G1_MAIZE (13-476): 3.66e-89: 285: 18.67		A0A1D6IQ85_MAIZE (6-1617): 0: 2658: 56.96
+	Sc
		604404 GGA2_YEAST (8-463): 3.74e-83: 269: 18.34		CLH_YEAST (5-1648): 0: 2443: 49.79
+	Sc
		604476 GGA1_YEAST (8-435): 2.46e-73: 242: 19.28		CLH_YEAST (5-1648): 0: 2443: 49.79