HitPredict

Interactor 1: CIAO1 (O76071)
Probable cytosolic iron-sulfur protein assembly protein CIAO1 (WD repeat-containing protein 39)
Gene: CIAO1

Interactor 2: TBL2 (Q9Y4P3)
Transducin beta-like protein 2 (WS beta-transducin repeats protein) (WS-betaTRP) (Williams-Beuren syndrome chromosomal region 13 protein)
Gene: TBL2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 339 Hs			1 447
+	Hs
		282843 CIAO1_HUMAN (1-337): 6.29e-105: 312: 100.00		LIS1_HUMAN (3-218): 5.36e-51: 179: 11.86
+	Hs
		282871 CIAO1_HUMAN (1-337): 6.29e-105: 312: 100.00		WDR5_HUMAN (4-165): 6.22e-31: 123: 8.93
+	Hs
		282789 CIAO1_HUMAN (1-337): 6.29e-105: 312: 100.00		CIAO1_HUMAN (81-215): 3.8e-16: 81.1: 18.12
+	Hs
		1240442 POC1B_HUMAN (92-339): 1.04e-59: 200: 20.97		POC1A_HUMAN (223-446): 2.09e-55: 190: 15.56
+	Hs
		245633 TBL1R_HUMAN (3-283): 1.27e-63: 211: 25.52		TBL1X_HUMAN (3-260): 4.69e-45: 166: 13.36
+	Dm
		1358845 WDS_DROME (137-339): 1.46e-47: 165: 20.69		WDS_DROME (222-447): 4.81e-53: 183: 16.74
+	Hs
		929579 POC1B_HUMAN (92-339): 1.04e-59: 200: 20.97		RACK1_HUMAN (266-445): 3.22e-20: 92.7: 16.30
+	Hs
		903418 FBXW7_HUMAN (3-217): 6.6e-46: 167: 19.73		WDR5_HUMAN (4-165): 6.22e-31: 123: 8.93
+	Hs
		792949 WDR5_HUMAN (225-339): 4.64e-18: 85.5: 15.65		LIS1_HUMAN (3-218): 5.36e-51: 179: 11.86
+	Hs
		929603 FBXW7_HUMAN (3-217): 6.6e-46: 167: 19.73		RACK1_HUMAN (266-445): 3.22e-20: 92.7: 16.30
+	Sp
		999838 TUP11_SCHPO (175-339): 1.79e-29: 120: 15.76		TUP11_SCHPO (1-167): 6.01e-35: 139: 8.38
+	Ca
		483033 TUP1_CANAL (180-338): 4.8e-28: 115: 18.87		TUP1_CANAL (327-446): 7.32e-27: 114: 10.53
+	Hs
		903551 NLE1_HUMAN (226-339): 2.65e-18: 87.5: 14.91		WDR5_HUMAN (4-165): 6.22e-31: 123: 8.93
+	Hs
		878165 SEC13_HUMAN (28-281): 8.06e-19: 87.4: 29.64		WDR5_HUMAN (4-165): 6.22e-31: 123: 8.93
+	Hs
		903077 WDR5_HUMAN (225-339): 4.64e-18: 85.5: 15.65		WDR5_HUMAN (4-165): 6.22e-31: 123: 8.93
+	Sc
		744605 TAF5_YEAST (124-339): 2.22e-35: 138: 19.48		TAF5_YEAST (269-419): 6.91e-11: 66.4: 17.61
+	Sp
		999842 TUP11_SCHPO (175-339): 1.79e-29: 120: 15.76		TUP12_SCHPO (5-121): 5.73e-16: 82.1: 13.95
+	Hs
		929692 NLE1_HUMAN (226-339): 2.65e-18: 87.5: 14.91		RACK1_HUMAN (266-445): 3.22e-20: 92.7: 16.30
+	Hs
		1346954 NLE1_HUMAN (226-339): 2.65e-18: 87.5: 14.91		NLE1_HUMAN (356-445): 8.01e-19: 90.6: 15.56