Interactor 1: LRP6 (O75581)
Low-density lipoprotein receptor-related protein 6 (LRP-6)
Gene: LRP6
Interactor 2: HGF (P14210)
Hepatocyte growth factor (Hepatopoietin-A) (Scatter factor) (SF) [Cleaved into: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain]
Gene: HGF
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.691 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33961781 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | FXa_inhibition~Trypsin, Ldl_recept_a~Trypsin |
| Common GO terms | GO:0005102 - signaling receptor binding GO:0005576 - extracellular region GO:0045944 - positive regulation of transcription by RNA polymerase II |
| Homologous interactions | 10 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
